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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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May 14, 2013
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1Institute for Molecular Cardiovascular Research,RWTH Aachen University, 2Institute for Textile Technology and Mechanical Engineering,RWTH Aachen University, 3Institute for Applied Medical Engineering,Helmholtz-Institute of RWTH Aachen University, 4Department of Experimental Molecular Imaging,RWTH Aachen University, 5Department of Oral and Maxillofacila Surgery,RWTH Aachen University
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A model of stent implantation in mouse carotid artery is described. Compared to other similar methods, this procedure is very rapid, simple and accessible, offering the possibility to study in a convenient way the vascular wall reaction to different drug-eluting stents and the molecular mechanisms of restenosis.
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Simsekyilmaz, S., Schreiber, F., Weinandy, S., Gremse, F., Sönmez, T. T., Liehn, E. A. A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis. J. Vis. Exp. (75), e50233, doi:10.3791/50233 (2013).
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