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Stereotaxic Surgery for Excitotoxic Lesion of Specific Brain Areas in the Adult Rat
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12:45 min
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July 19, 2012
DOI:
1Helen Wills Neuroscience Institute,University of California Berkeley, 2Office of Laboratory Animal Care,University of California Berkeley, 3McGovern Institute for Brain Research & The Department of Brain and Cognitive Science,Massachusetts Institute of Technology, 4Integrative Biology Department,University of California Berkeley
Summary
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Targeted ablation of specific brain region(s) by infusion of an excitotoxin using stereotaxic coordinates is described. This technique could also be adapted for infusion of other chemicals into the rat brain.
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Kirby, E. D., Jensen, K., Goosens, K. A., Kaufer, D. Stereotaxic Surgery for Excitotoxic Lesion of Specific Brain Areas in the Adult Rat. J. Vis. Exp. (65), e4079, doi:10.3791/4079 (2012).
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