A murine model of neuromuscular electrical stimulation (NMES), a safe and inexpensive clinical modality, to the anterior compartment muscles is described. This model has the advantage of modifying a readily available clinical device for the purpose of eliciting targeted and specific muscle contractions in mice.
Ambrosio, F., Fitzgerald, G. K., Ferrari, R., Distefano, G., Carvell, G. A Murine Model of Muscle Training by Neuromuscular Electrical Stimulation. J. Vis. Exp. (63), e3914, doi:10.3791/3914 (2012).