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Investigating the Neural Mechanisms of Aware and Unaware Fear Memory with fMRI
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October 06, 2011
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A methodology to investigate the neural mechanisms that support aware and unaware memory processes during fear conditioning is described. This method monitors blood oxygen level dependent (BOLD) functional magnetic resonance imaging, skin conductance response, and unconditioned stimulus expectancy during Pavlovian fear conditioning to assess the neural correlates of distinct memory processes.
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FMRIPavlovian Fear ConditioningNeural MechanismsAware Fear MemoryUnaware Fear MemoryFMRIAssociative LearningBrain ActivityHuman BehaviorAutonomic ResponsesSkin Conductance Response (SCR)ConditioningUnconditioned Stimulus (UCS) ExpectanciesConditioned Response (CR)Unconditioned Response (UCR)Cognitive FunctionsUCS Expectancy MeasuresTrial-to-trial BasisInterferenceForgettingMonitoring Autonomic And Behavioral Responses
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Knight, D. C., Wood, K. H. Investigating the Neural Mechanisms of Aware and Unaware Fear Memory with fMRI. J. Vis. Exp. (56), e3083, doi:10.3791/3083 (2011).
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