JOVE JOURNAL

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Showing 301 - 312 in 611 videos.

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

Kiichi Sugimoto^1,2, Hirotaka Momose², Tomoaki Ito^1,3, Hajime Orita³, Koichi Sato³, Kazuhiro Sakamoto², Malcolm V. Brock¹

¹Department of Surgery, The Sidney Kimmel Comprehensive Cancer Center,Johns Hopkins University School of Medicine, ²Department of Coloproctological Surgery,Juntendo University Faculty of Medicine, ³Department of Surgery,Juntendo University Shizuoka Hospital

Journal (Cancer Research)

Detection of Cell-Free DNA in Blood Plasma Samples of Cancer Patients

Vikrant Palande¹, Dorith Raviv Shay¹, MILANA Frenkel-Morgenstern^1,2,3

¹Cancer Genomics and BioComputing of Complex Diseases laboratory, The Azrieli Faculty of Medicine,Bar-Ilan University, ²The Data Science Institute,Bar-Ilan University, ³The Dangoor Centre For Personalized Medicine,Bar-Ilan University

Journal (Cancer Research)

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Blake E. Hildreth III¹, Charlotte Palmer², Matthew J. Allen²

¹Department of Pathology and O'Neal Comprehensive Cancer Center,University of Alabama at Birmingham, ²Surgical Discovery Centre, Department of Veterinary Medicine,University of Cambridge

Journal (Cancer Research)

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq

Ashwin Narayanan¹, Enrique Blanco-Carmona², Engin Demirdizen¹, Xueyuan Sun^1,3, Christel Herold-Mende⁴, Matthias Schlesner², Sevin Turcan¹

¹Neurology Clinic and National Center for Tumor Diseases,University Hospital Heidelberg, ²Bioinformatics and Omics Data Analytics,German Cancer Research Center (DKFZ), ³Clinical Cooperation Unit Neurooncology,German Cancer Research Center (DKFZ), ⁴Division of Experimental Neurosurgery, Department of Neurosurgery,University of Heidelberg, INF 400, Heidelberg, Germany

Journal (Cancer Research)

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

C. Ryan Oliver*^1,2, Trisha M. Westerhof*^1,2, Maria G. Castro^2,3,4, Sofia D. Merajver^1,2

¹Department of Internal Medicine,University of Michigan Ann Arbor, ²Rogel Cancer Center,University of Michigan Ann Arbor, ³Department of Neurosurgery,University of Michigan Ann Arbor, ⁴Department of Cell and Developmental Biology,University of Michigan Ann Arbor

Journal (Cancer Research)

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Stephan Ellmann¹, Lisa Seyler¹, Clarissa Gillmann², Vanessa Popp¹, Christoph Treutlein¹, Aline Bozec³, Michael Uder¹, Tobias Bäuerle¹

¹Department of Radiology, University Hospital Erlangen,Friedrich-Alexander Universität Erlangen-Nürnberg, ²Department of Medical Physics in Radiation Oncology,German Cancer Research Center, ³Department of Internal Medicine 3, University Hospital Erlangen,Friedrich-Alexander Universität Erlangen-Nürnberg

Journal (Cancer Research)

A Biomimetic Model for Liver Cancer to Study Tumor-Stroma Interactions in a 3D Environment with Tunable Bio-Physical Properties

Carlemi Calitz¹, Nataša Pavlović¹, Jenny Rosenquist², Claudia Zagami¹, Ayan Samanta², Femke Heindryckx¹

¹Department of Medical Cell Biology,Uppsala University, ²Polymer Chemistry, Department of Chemistry-Ångström Laboratory,Uppsala University

Journal (Cancer Research)

Assays for Validating Histone Acetyltransferase Inhibitors

Aaron R. Waddell¹, Daiqing Liao¹

¹Department of Anatomy and Cell Biology, and UF Health Cancer Center,University of Florida College of Medicine

Journal (Cancer Research)

Perfusion and Inflation of the Mouse Lung for Tumor Histology

Mackenzie L. Davenport¹, Taylor P. Sherrill², Timothy S. Blackwell², Mick D. Edmonds¹

¹Department of Genetics,University of Alabama at Birmingham, ²Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine,Vanderbilt University School of Medicine

Journal (Cancer Research)

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Piyan Zhang¹, Irina V. Kovtun^1,2

¹Center for Individualized Medicine,Mayo Clinic, ²Department of Molecular Pharmacology and Experimental Therapeutics,Mayo Clinic

Journal (Cancer Research)

Management of Respiratory Motion Artefacts in ¹⁸F-fluorodeoxyglucose Positron Emission Tomography using an Amplitude-Based Optimal Respiratory Gating Algorithm

Willem Grootjans¹, Peter Kok², Jurrian Butter², Erik Aarntzen²

¹Department of Radiology,Leiden University Medical Centre, ²Department of Radiology and Nuclear Medicine,Radboud University Medical Centre

Journal (Cancer Research)

Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres

Chun-Chia Cheng¹, Po-Jui Hsu⁴, Zong-Lin Sie¹, Fang-Hsin Chen^1,2,3

¹Radiation Biology Research Center, Institute for Radiological Research,Chang Gung University, Chang Gung Memorial Hospital at Linkou, ²Department of Medical Imaging and Radiological Sciences,Chang Gung University, ³Department of Radiation Oncology,Chang Gung Memorial Hospital, ⁴Department of Laboratory Medicine,Mackay Memorial Hospital

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