Stella E. Tsirka Department of Pharmacological Sciences Stony Brook University Biography Publications Institution JoVE Articles Stella E. Tsirka has not added a biography. If you are Stella E. Tsirka and would like to personalize this page please email our Author Liaison for assistance. Publications Inflammatory Stress Response in A549 Cells As a Result of Exposure to Coal: Evidence for the Role of Pyrite in Coal Workers' Pneumoconiosis Pathogenesis Chemosphere. Jul, 2013 | Pubmed ID: 23895739 Members of the High Mobility Group B Protein Family Are Dynamically Expressed in Embryonic Neural Stem Cells Proteome Science. 2013 | Pubmed ID: 23621913 Microglia Actively Regulate the Number of Functional Synapses PloS One. 2013 | Pubmed ID: 23393609 The Annexin A2/S100A10 System in Health and Disease: Emerging Paradigms Journal of Biomedicine & Biotechnology. 2012 | Pubmed ID: 23193360 Inflammation Modulates Expression of Laminin in the Central Nervous System Following Ischemic Injury Journal of Neuroinflammation. 2012 | Pubmed ID: 22759265 P53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis Cell. Jun, 2012 | Pubmed ID: 22726440 Microglial Inhibitory Factor (MIF/TKP) Mitigates Secondary Damage Following Spinal Cord Injury Neurobiology of Disease. Sep, 2012 | Pubmed ID: 22613732 Tuftsin Promotes an Anti-inflammatory Switch and Attenuates Symptoms in Experimental Autoimmune Encephalomyelitis PloS One. 2012 | Pubmed ID: 22529957 Quantification of Particle-induced Inflammatory Stress Response: a Novel Approach for Toxicity Testing of Earth Materials Geochemical Transactions. 2012 | Pubmed ID: 22513118 The CCL2-CCR2 System Affects the Progression and Clearance of Intracerebral Hemorrhage Glia. May, 2012 | Pubmed ID: 22419223 Neuroimaging in Animal Seizure Models with (18)FDG-PET Epilepsy Research and Treatment. 2011 | Pubmed ID: 22937232 Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis Neurology Research International. 2011 | Pubmed ID: 22203900 Axonal Regrowth After Spinal Cord Injury Via Chondroitinase and the Tissue Plasminogen Activator (tPA)/plasmin System The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011 | Pubmed ID: 22016526 Annexin A2 Promotes Glioma Cell Invasion and Tumor Progression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011 | Pubmed ID: 21976520 Mouse MCP1 C-terminus Inhibits Human MCP1-induced Chemotaxis and BBB Compromise Journal of Neurochemistry. Jul, 2011 | Pubmed ID: 21615737 Truncation of Monocyte Chemoattractant Protein 1 by Plasmin Promotes Blood-brain Barrier Disruption Journal of Cell Science. May, 2011 | Pubmed ID: 21486949 Microglia/macrophages Promote Glioma Progression Glia. Mar, 2011 | Pubmed ID: 21264953 Microglia Shape Adult Hippocampal Neurogenesis Through Apoptosis-coupled Phagocytosis Cell Stem Cell. Oct, 2010 | Pubmed ID: 20887954 The C Terminus of Mouse Monocyte Chemoattractant Protein 1 (MCP1) Mediates MCP1 Dimerization While Blocking Its Chemotactic Potency The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20682771 Tissue Plasminogen Activator Alters Intracellular Sequestration of Zinc Through Interaction with the Transporter ZIP4 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2010 | Pubmed ID: 20463217 Microglial Ablation and Lipopolysaccharide Preconditioning Affects Pilocarpine-induced Seizures in Mice Neurobiology of Disease. Jul, 2010 | Pubmed ID: 20382223 Decreased Serotonin Levels Associated with Behavioral Disinhibition in Tissue Plasminogen Activator Deficient (tPA-/-) Mice Brain Research. Apr, 2010 | Pubmed ID: 20156421 Endothelial NOS-deficient Mice Reveal Dual Roles for Nitric Oxide During Experimental Autoimmune Encephalomyelitis Glia. Aug, 2009 | Pubmed ID: 19170181 Tissue-type Plasminogen Activator As a Therapeutic Target in Stroke Expert Opinion on Therapeutic Targets. Feb, 2008 | Pubmed ID: 18208365 TPA-mediated Generation of Plasmin is Catalyzed by the Proteoglycan NG2 Glia. Jan, 2008 | Pubmed ID: 18000864 A Novel Approach for Imaging Brain-behavior Relationships in Mice Reveals Unexpected Metabolic Patterns During Seizures in the Absence of Tissue Plasminogen Activator NeuroImage. Oct, 2007 | Pubmed ID: 17707126 Modulation of Microglial/macrophage Activation by Macrophage Inhibitory Factor (TKP) or Tuftsin (TKPR) Attenuates the Disease Course of Experimental Autoimmune Encephalomyelitis BMC Immunology. 2007 | Pubmed ID: 17634104 Brain Edema After Intracerebral Hemorrhage: Mechanisms, Treatment Options, Management Strategies, and Operative Indications Neurosurgical Focus. 2007 | Pubmed ID: 17613237 Nitric Oxide Synthase Isoforms Undertake Unique Roles During Excitotoxicity Stroke; a Journal of Cerebral Circulation. Jun, 2007 | Pubmed ID: 17446423 Proteolytic Activation of Monocyte Chemoattractant Protein-1 by Plasmin Underlies Excitotoxic Neurodegeneration in Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2007 | Pubmed ID: 17301181 Nitric Oxide Mediates Neurodegeneration and Breakdown of the Blood-brain Barrier in TPA-dependent Excitotoxic Injury in Mice Journal of Cell Science. Jan, 2006 | Pubmed ID: 16410551 PET Imaging of Glucose Metabolism in a Mouse Model of Temporal Lobe Epilepsy Synapse (New York, N.Y.). Feb, 2006 | Pubmed ID: 16320304 Contribution of Extracellular Proteolysis and Microglia to Intracerebral Hemorrhage Neurocritical Care. 2005 | Pubmed ID: 16159103 Fibrin-modifying Serine Proteases Thrombin, TPA, and Plasmin in Ischemic Stroke: a Review Glia. Jun, 2005 | Pubmed ID: 15846799 Neuroprotection by Inhibition of Matrix Metalloproteinases in a Mouse Model of Intracerebral Haemorrhage Brain : a Journal of Neurology. Jul, 2005 | Pubmed ID: 15800021 Phospholipase D1-promoted Release of Tissue Plasminogen Activator Facilitates Neurite Outgrowth The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2005 | Pubmed ID: 15716416 Tuftsin Fragment 1-3 is Beneficial when Delivered After the Induction of Intracerebral Hemorrhage Stroke; a Journal of Cerebral Circulation. Mar, 2005 | Pubmed ID: 15692122 Tissue Plasminogen Activator and Glial Function Glia. Jan, 2005 | Pubmed ID: 15494978 Increased Expression of Two Phospholipase D Isoforms During Experimentally Induced Hippocampal Mossy Fiber Outgrowth Glia. Apr, 2004 | Pubmed ID: 14999815 Modulation of Zinc Toxicity by Tissue Plasminogen Activator Molecular and Cellular Neurosciences. Jan, 2004 | Pubmed ID: 14962749 Protective Role of Tuftsin Fragment 1-3 in an Animal Model of Intracerebral Hemorrhage Annals of Neurology. Nov, 2003 | Pubmed ID: 14595655 Cell Type-specific Roles for Tissue Plasminogen Activator Released by Neurons or Microglia After Excitotoxic Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2003 | Pubmed ID: 12716930 Involvement of Tissue Plasminogen Activator in Onset and Effector Phases of Experimental Allergic Encephalomyelitis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2002 | Pubmed ID: 12486171 Microglial Activation and Recruitment, but Not Proliferation, Suffice to Mediate Neurodegeneration Cell Death and Differentiation. Aug, 2002 | Pubmed ID: 12107823 Tissue Plasminogen Activator As a Modulator of Neuronal Survival and Function Biochemical Society Transactions. Apr, 2002 | Pubmed ID: 12023855 Extracellular Proteases and Neuronal Cell Death Cellular and Molecular Biology (Noisy-le-Grand, France). Mar, 2002 | Pubmed ID: 11990450 Tissue Plasminogen Activator Mediates Microglial Activation Via Its Finger Domain Through Annexin II The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002 | Pubmed ID: 11978811 Partial Rescue of Neural Apoptosis in the Lurcher Mutant Mouse Through Elimination of Tissue Plasminogen Activator Development (Cambridge, England). Apr, 2002 | Pubmed ID: 11934869 Culturing Microglia from the Neonatal and Adult Central Nervous System Robert Bronstein*1,2, Luisa Torres*2,3, Jillian C. Nissen*2,3, Stella E. Tsirka2 1Program in Neuroscience, Stony Brook University, 2Department of Pharmacological Sciences, Stony Brook University, 3Program in Molecular and Cellular Pharmacology, Stony Brook University JoVE 50647 면역학 및 감염병학
Culturing Microglia from the Neonatal and Adult Central Nervous System Robert Bronstein*1,2, Luisa Torres*2,3, Jillian C. Nissen*2,3, Stella E. Tsirka2 1Program in Neuroscience, Stony Brook University, 2Department of Pharmacological Sciences, Stony Brook University, 3Program in Molecular and Cellular Pharmacology, Stony Brook University JoVE 50647 면역학 및 감염병학