Sina Bavari Division of Molecular and Translational Sciences US Army Medical Research Institute of Infectious Diseases Biography Publications Institution JoVE Articles Sina Bavari has not added a biography. If you are Sina Bavari and would like to personalize this page please email our Author Liaison for assistance. Publications High-Content Image-Based Screening of a Signal Transduction Pathway Inhibitor Small-Molecule Library Against Highly Pathogenic RNA Viruses Journal of Biomolecular Screening. Oct, 2014 | Pubmed ID: 25342145 Recent Advances in Botulinum Neurotoxin Inhibitor Development Current Topics in Medicinal Chemistry. Oct, 2014 | Pubmed ID: 25335887 Vaccine Adjuvant Uses of Poly-IC and Derivatives Expert Review of Vaccines. Oct, 2014 | Pubmed ID: 25308798 Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names Viruses. Sep, 2014 | Pubmed ID: 25256396 High Content Image-based Screening of a Protease Inhibitor Library Reveals Compounds Broadly Active Against Rift Valley Fever Virus and Other Highly Pathogenic RNA Viruses PLoS Neglected Tropical Diseases. Aug, 2014 | Pubmed ID: 25144302 HSPA5 is an Essential Host Factor for Ebola Virus Infection Antiviral Research. Sep, 2014 | Pubmed ID: 25017472 Applications of In Vivo Imaging in the Evaluation of the Pathophysiology of Viral and Bacterial Infections and in Development of Countermeasures to BSL3/4 Pathogens Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jul, 2014 | Pubmed ID: 25008802 Multi-faceted Proteomic Characterization of Host Protein Complement of Rift Valley Fever Virus Virions and Identification of Specific Heat Shock Proteins, Including HSP90, As Important Viral Host Factors PloS One. 2014 | Pubmed ID: 24809507 A High-content Imaging Assay for the Quantification of the Burkholderia Pseudomallei Induced Multinucleated Giant Cell (MNGC) Phenotype in Murine Macrophages BMC Microbiology. 2014 | Pubmed ID: 24750902 Second Generation Steroidal 4-aminoquinolines Are Potent, Dual-target Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease and P. Falciparum Malaria Journal of Medicinal Chemistry. May, 2014 | Pubmed ID: 24742203 Induced IL-10 Splice Altering Approach to Antiviral Drug Discovery Nucleic Acid Therapeutics. Jun, 2014 | Pubmed ID: 24655055 Marburgvirus Hijacks Nrf2-dependent Pathway by Targeting Nrf2-negative Regulator Keap1 Cell Reports. Mar, 2014 | Pubmed ID: 24630992 TrkA in Vivo Function is Negatively Regulated by Ubiquitination The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2014 | Pubmed ID: 24623787 Protection Against Filovirus Diseases by a Novel Broad-spectrum Nucleoside Analogue BCX4430 Nature. Apr, 2014 | Pubmed ID: 24590073 Toll-like Receptor Agonist Augments Virus-like Particle-mediated Protection from Ebola Virus with Transient Immune Activation PloS One. 2014 | Pubmed ID: 24586996 Alveolar Macrophages Infected with Ames or Sterne Strain of Bacillus Anthracis Elicit Differential Molecular Expression Patterns PloS One. 2014 | Pubmed ID: 24516547 Recent Developments in Cell-based Assays and Stem Cell Technologies for Botulinum Neurotoxin Research and Drug Discovery Expert Review of Molecular Diagnostics. Mar, 2014 | Pubmed ID: 24450833 Reactive Oxygen Species Activate NFκB (p65) and P53 and Induce Apoptosis in RVFV Infected Liver Cells Virology. Jan, 2014 | Pubmed ID: 24418562 Virus Nomenclature Below the Species Level: a Standardized Nomenclature for Filovirus Strains and Variants Rescued from CDNA Archives of Virology. May, 2014 | Pubmed ID: 24190508 Ebola Virus-like Particles Stimulate Type I Interferons and Proinflammatory Cytokine Expression Through the Toll-like Receptor and Interferon Signaling Pathways Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Feb, 2014 | Pubmed ID: 24102579 Potent and Broad-spectrum Antibacterial Activity of Indole-based Bisamidine Antibiotics: Synthesis and SAR of Novel Analogs of MBX 1066 and MBX 1090 Bioorganic & Medicinal Chemistry. Dec, 2013 | Pubmed ID: 24239389 Nonhuman Transferrin Receptor 1 is an Efficient Cell Entry Receptor for Ocozocoautla De Espinosa Virus Journal of Virology. Dec, 2013 | Pubmed ID: 24109228 Anthrax Toxin-induced Rupture of Artificial Lipid Bilayer Membranes The Journal of Chemical Physics. Aug, 2013 | Pubmed ID: 23947891 Characterization of the Burkholderia Thailandensis SOS Response by Using Whole-transcriptome Shotgun Sequencing Applied and Environmental Microbiology. Oct, 2013 | Pubmed ID: 23872555 4-Amino-7-chloroquinolines: Probing Ligand Efficiency Provides Botulinum Neurotoxin Serotype A Light Chain Inhibitors with Significant Antiprotozoal Activity Journal of Medicinal Chemistry. Jul, 2013 | Pubmed ID: 23815186 Crimean-Congo Hemorrhagic Fever Virus Utilizes a Clathrin- and Early Endosome-dependent Entry Pathway Virology. Sep, 2013 | Pubmed ID: 23791227 The C Terminus of the Catalytic Domain of Type A Botulinum Neurotoxin May Facilitate Product Release from the Active Site The Journal of Biological Chemistry. Aug, 2013 | Pubmed ID: 23779108 IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus Journal of Virology. Aug, 2013 | Pubmed ID: 23720721 Small Molecule Inhibitors of ER α-glucosidases Are Active Against Multiple Hemorrhagic Fever Viruses Antiviral Research. Jun, 2013 | Pubmed ID: 23578725 A Systematic Screen of FDA-approved Drugs for Inhibitors of Biological Threat Agents PloS One. 2013 | Pubmed ID: 23577127 Predictive Systems Biology Approach to Broad-spectrum, Host-directed Drug Target Discovery in Infectious Diseases Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2013 | Pubmed ID: 23424108 The International Code of Virus Classification and Nomenclature (ICVCN): Proposal for Text Changes for Improved Differentiation of Viral Taxa and Viruses Archives of Virology. Jul, 2013 | Pubmed ID: 23417351 Characterization of a Putative Filovirus Vaccine: Virus-like Particles Virologica Sinica. Apr, 2013 | Pubmed ID: 23385315 Integrating High-content Imaging and Chemical Genetics to Probe Host Cellular Pathways Critical for Yersinia Pestis Infection PloS One. 2013 | Pubmed ID: 23383093 Virus Nomenclature Below the Species Level: a Standardized Nomenclature for Laboratory Animal-adapted Strains and Variants of Viruses Assigned to the Family Filoviridae Archives of Virology. Jun, 2013 | Pubmed ID: 23358612 Bis-imidazolinylindoles Are Active Against Methicillin-resistant Staphylococcus Aureus and Multidrug-resistant Mycobacterium Tuberculosis The Journal of Antibiotics. Jan, 2013 | Pubmed ID: 23149517 Virus Nomenclature Below the Species Level: a Standardized Nomenclature for Natural Variants of Viruses Assigned to the Family Filoviridae Archives of Virology. Jan, 2013 | Pubmed ID: 23001720 The International Code of Virus Classification and Nomenclature (ICVCN): Proposal to Delete Rule 3.41 Archives of Virology. Jan, 2013 | Pubmed ID: 22932924 The Impact of Regulations, Safety Considerations and Physical Limitations on Research Progress at Maximum Biocontainment Viruses. Dec, 2012 | Pubmed ID: 23342380 Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies Viruses. Dec, 2012 | Pubmed ID: 23223188 Ebola Virus Genome Plasticity As a Marker of Its Passaging History: a Comparison of in Vitro Passaging to Non-human Primate Infection PloS One. 2012 | Pubmed ID: 23209706 Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections Viruses. Nov, 2012 | Pubmed ID: 23202506 High Content Image Based Analysis Identifies Cell Cycle Inhibitors As Regulators of Ebola Virus Infection Viruses. Oct, 2012 | Pubmed ID: 23202445 Shedding Light on Filovirus Infection with High-content Imaging Viruses. Aug, 2012 | Pubmed ID: 23012631 A Limited Structural Modification Results in a Significantly More Efficacious Diazachrysene-based Filovirus Inhibitor Viruses. Aug, 2012 | Pubmed ID: 23012625 Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus Anthracis Nucleic Acid Therapeutics. Oct, 2012 | Pubmed ID: 22978365 High-throughput Screen Using a Single-cell Tyrosine Phosphatase Assay Reveals Biologically Active Inhibitors of Tyrosine Phosphatase CD45 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22891353 Therapeutics for Filovirus Infection: Traditional Approaches and Progress Towards in Silico Drug Design Expert Opinion on Drug Discovery. Oct, 2012 | Pubmed ID: 22873527 Assembly of Ebola Virus Matrix Protein VP40 is Regulated by Latch-like Properties of N and C Terminal Tails PloS One. 2012 | Pubmed ID: 22792204 Drug Discovery Technologies and Strategies for Machupo Virus and Other New World Arenaviruses Expert Opinion on Drug Discovery. Jul, 2012 | Pubmed ID: 22607481 The Synthesis of 2,5-bis(4-amidinophenyl)thiophene Derivatives Providing Submicromolar-range Inhibition of the Botulinum Neurotoxin Serotype A Metalloprotease European Journal of Medicinal Chemistry. Jul, 2012 | Pubmed ID: 22516424 Advanced Morpholino Oligomers: a Novel Approach to Antiviral Therapy Antiviral Research. Apr, 2012 | Pubmed ID: 22353544 Identification of an Antioxidant Small-molecule with Broad-spectrum Antiviral Activity Antiviral Research. Jan, 2012 | Pubmed ID: 22027648 Novel Benzimidazole Inhibitors of Botulinum Neurotoxin/A Display Enzyme and Cell-Based Potency The Botulinum Journal. 2011 | Pubmed ID: 23205055 Nonhuman Primates As Models for the Discovery and Development of Ebolavirus Therapeutics Expert Opinion on Drug Discovery. Mar, 2011 | Pubmed ID: 22647202 Humanized Mice As a Preclinical Tool for Infectious Disease and Biomedical Research Annals of the New York Academy of Sciences. Dec, 2011 | Pubmed ID: 22211979 Time-dependent Botulinum Neurotoxin Serotype A Metalloprotease Inhibitors Bioorganic & Medicinal Chemistry. Dec, 2011 | Pubmed ID: 22082667 Evaluation of Perceived Threat Differences Posed by Filovirus Variants Biosecurity and Bioterrorism : Biodefense Strategy, Practice, and Science. Dec, 2011 | Pubmed ID: 22070137 Post-intoxication Inhibition of Botulinum Neurotoxin Serotype A Within Neurons by Small-molecule, Non-peptidic Inhibitors Toxins. Mar, 2011 | Pubmed ID: 22069707 Correlates of Immunity to Filovirus Infection Viruses. Jul, 2011 | Pubmed ID: 21994766 Machupo Virus Glycoprotein Determinants for Human Transferrin Receptor 1 Binding and Cell Entry PloS One. 2011 | Pubmed ID: 21750710 Ebolavirus Delta-peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry Journal of Virology. Sep, 2011 | Pubmed ID: 21697477 A STAT-1 Knockout Mouse Model for Machupo Virus Pathogenesis Virology Journal. 2011 | Pubmed ID: 21672221 Filovirus Vaccines Human Vaccines. Jun, 2011 | Pubmed ID: 21519188 Development and Characterization of Rabbit and Mouse Antibodies Against Ebolavirus Envelope Glycoproteins Journal of Virological Methods. Jun, 2011 | Pubmed ID: 21513741 Inhibition of Ebola Virus Entry by a C-peptide Targeted to Endosomes The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21454542 Crimean-Congo Hemorrhagic Fever: Current and Future Prospects of Vaccines and Therapies Antiviral Research. May, 2011 | Pubmed ID: 21362441 Embryonic Stem Cell-derived Motoneurons Provide a Highly Sensitive Cell Culture Model for Botulinum Neurotoxin Studies, with Implications for High-throughput Drug Discovery Stem Cell Research. May, 2011 | Pubmed ID: 21353660 Ebola Virus Glycoprotein Fc Fusion Protein Confers Protection Against Lethal Challenge in Vaccinated Mice Vaccine. Apr, 2011 | Pubmed ID: 21329775 Key Genomic Changes Necessary for an in Vivo Lethal Mouse Marburgvirus Variant Selection Process Journal of Virology. Apr, 2011 | Pubmed ID: 21289122 Identification of a Small-molecule Entry Inhibitor for Filoviruses Journal of Virology. Apr, 2011 | Pubmed ID: 21270170 A Chemotype That Inhibits Three Unrelated Pathogenic Targets: the Botulinum Neurotoxin Serotype A Light Chain, P. Falciparum Malaria, and the Ebola Filovirus Journal of Medicinal Chemistry. Mar, 2011 | Pubmed ID: 21265542 Distinct Patterns of IFITM-mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus PLoS Pathogens. 2011 | Pubmed ID: 21253575 Alkylated Porphyrins Have Broad Antiviral Activity Against Hepadnaviruses, Flaviviruses, Filoviruses, and Arenaviruses Antimicrobial Agents and Chemotherapy. Feb, 2011 | Pubmed ID: 21135183 Generation and Characterization of High Affinity Human Monoclonal Antibodies That Neutralize Staphylococcal Enterotoxin B Journal of Immune Based Therapies and Vaccines. 2010 | Pubmed ID: 21176153 Pharmacophore Refinement Guides the Rational Design of Nanomolar-Range Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease ACS Medicinal Chemistry Letters. Oct, 2010 | Pubmed ID: 21116458 Analysis of Botulinum Neurotoxin Serotype A Metalloprotease Inhibitors: Analogs of a Chemotype for Therapeutic Development in the Context of a Three-Zone Pharmacophore Open Access Bioinformatics. Apr, 2010 | Pubmed ID: 21103387 Assembly of a Functional Machupo Virus Polymerase Complex Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 20978208 Advanced Antisense Therapies for Postexposure Protection Against Lethal Filovirus Infections Nature Medicine. Sep, 2010 | Pubmed ID: 20729866 The Osmolyte Trimethylamine N-oxide (TMAO) Increases the Proteolytic Activity of Botulinum Neurotoxin Light Chains A, B, and E: Implications for Enhancing Analytical Assay Sensitivity Journal of Biomolecular Screening. Sep, 2010 | Pubmed ID: 20720092 Identification of Essential Filovirion-associated Host Factors by Serial Proteomic Analysis and RNAi Screen Molecular & Cellular Proteomics : MCP. Dec, 2010 | Pubmed ID: 20702783 Infectious Lassa Virus, but Not Filoviruses, is Restricted by BST-2/tetherin Journal of Virology. Oct, 2010 | Pubmed ID: 20686043 Development of High-content Imaging Assays for Lethal Viral Pathogens Journal of Biomolecular Screening. Aug, 2010 | Pubmed ID: 20639507 Comparative in Vitro Activity Profiles of Novel Bis-indole Antibacterials Against Gram-positive and Gram-negative Clinical Isolates Antimicrobial Agents and Chemotherapy. Sep, 2010 | Pubmed ID: 20625154 3D Visualization of HIV Transfer at the Virological Synapse Between Dendritic Cells and T Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20624966 Iterative Structure-based Peptide-like Inhibitor Design Against the Botulinum Neurotoxin Serotype A PloS One. 2010 | Pubmed ID: 20614028 Antiviral Activity of a Small-molecule Inhibitor of Filovirus Infection Antimicrobial Agents and Chemotherapy. May, 2010 | Pubmed ID: 20211898 Gaining Ground: Assays for Therapeutics Against Botulinum Neurotoxin Trends in Microbiology. Apr, 2010 | Pubmed ID: 20202845 Ebola Virus Uses Clathrin-mediated Endocytosis As an Entry Pathway Virology. May, 2010 | Pubmed ID: 20202662 Efflux-mediated Bis-indole Resistance in Staphylococcus Aureus Reveals Differential Substrate Specificities for MepA and MepR Bioorganic & Medicinal Chemistry. Mar, 2010 | Pubmed ID: 20188576 Synthesis and Biological Evaluation of Botulinum Neurotoxin a Protease Inhibitors Journal of Medicinal Chemistry. Mar, 2010 | Pubmed ID: 20155918 Mechanisms and Consequences of Ebolavirus-induced Lymphocyte Apoptosis Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 20028660 Development of Cell-based Assays to Measure Botulinum Neurotoxin Serotype A Activity Using Cleavage-sensitive Antibodies Journal of Biomolecular Screening. Jan, 2010 | Pubmed ID: 19965805 Generation of Heterogeneous Memory T Cells by Live Attenuated Tularemia Vaccine in Humans Vaccine. Dec, 2009 | Pubmed ID: 19799845 Discovery of Common Marburgvirus Protective Epitopes in a BALB/c Mouse Model Virology Journal. 2009 | Pubmed ID: 19712478 Reduced Levels of Protein Tyrosine Phosphatase CD45 Protect Mice from the Lethal Effects of Ebola Virus Infection Cell Host & Microbe. Aug, 2009 | Pubmed ID: 19683682 Novel Broad-spectrum Bis-(imidazolinylindole) Derivatives with Potent Antibacterial Activities Against Antibiotic-resistant Strains Antimicrobial Agents and Chemotherapy. Oct, 2009 | Pubmed ID: 19635954 Development of a Broad-spectrum Antiviral with Activity Against Ebola Virus Antiviral Research. Sep, 2009 | Pubmed ID: 19523489 Filovirus Infections Journal of the American Veterinary Medical Association. May, 2009 | Pubmed ID: 19405883 Development and Characterization of a Mouse Model for Marburg Hemorrhagic Fever Journal of Virology. Jul, 2009 | Pubmed ID: 19369350 Reduced Expression of CD45 Protein-tyrosine Phosphatase Provides Protection Against Anthrax Pathogenesis The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19269962 Chemical Modifications of Antisense Morpholino Oligomers Enhance Their Efficacy Against Ebola Virus Infection Antimicrobial Agents and Chemotherapy. May, 2009 | Pubmed ID: 19223614 Three-dimensional Database Mining Identifies a Unique Chemotype That Unites Structurally Diverse Botulinum Neurotoxin Serotype A Inhibitors in a Three-zone Pharmacophore ChemMedChem. Dec, 2008 | Pubmed ID: 19006141 A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation Than SNAP-25 Substrate Structure (London, England : 1993). Oct, 2008 | Pubmed ID: 18940613 Sizing the Bacillus Anthracis PA63 Channel with Nonelectrolyte Poly(ethylene Glycols) Biophysical Journal. Aug, 2008 | Pubmed ID: 18645196 Novel 4-aminoquinolines Active Against Chloroquine-resistant and Sensitive P. Falciparum Strains That Also Inhibit Botulinum Serotype A Journal of Medicinal Chemistry. Aug, 2008 | Pubmed ID: 18637666 Monovalent Virus-like Particle Vaccine Protects Guinea Pigs and Nonhuman Primates Against Infection with Multiple Marburg Viruses Expert Review of Vaccines. May, 2008 | Pubmed ID: 18444889 Identification of Oxidative Stress and Toll-like Receptor 4 Signaling As a Key Pathway of Acute Lung Injury Cell. Apr, 2008 | Pubmed ID: 18423196 Functional CD8+ T Cell Responses in Lethal Ebola Virus Infection Journal of Immunology (Baltimore, Md. : 1950). Mar, 2008 | Pubmed ID: 18322215 Oligonucleotide Antiviral Therapeutics: Antisense and RNA Interference for Highly Pathogenic RNA Viruses Antiviral Research. Apr, 2008 | Pubmed ID: 18258313 Development of a Model for Marburgvirus Based on Severe-combined Immunodeficiency Mice Virology Journal. 2007 | Pubmed ID: 17961252 Ebola Virus-like Particle-based Vaccine Protects Nonhuman Primates Against Lethal Ebola Virus Challenge The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 17940980 Filovirus-like Particles Produced in Insect Cells: Immunogenicity and Protection in Rodents The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 17940979 Ebola Virus Inactivation with Preservation of Antigenic and Structural Integrity by a Photoinducible Alkylating Agent The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 17940961 Involvement of Vacuolar Protein Sorting Pathway in Ebola Virus Release Independent of TSG101 Interaction The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 17940959 A Refined Pharmacophore Identifies Potent 4-amino-7-chloroquinoline-based Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease Journal of Medicinal Chemistry. May, 2007 | Pubmed ID: 17417831 NKp30-dependent Cytolysis of Filovirus-infected Human Dendritic Cells Cellular Microbiology. Apr, 2007 | Pubmed ID: 17381429 Chemical Genetic Screening Identifies Critical Pathways in Anthrax Lethal Toxin-induced Pathogenesis Chemistry & Biology. Mar, 2007 | Pubmed ID: 17379140 Transcriptome Analysis of Human Immune Responses Following Live Vaccine Strain (LVS) Francisella Tularensis Vaccination Molecular Immunology. May, 2007 | Pubmed ID: 17349694 Primary Cultures of Embryonic Chicken Neurons for Sensitive Cell-based Assay of Botulinum Neurotoxin: Implications for Therapeutic Discovery Journal of Biomolecular Screening. Apr, 2007 | Pubmed ID: 17332092 Inhibition of Metalloprotease Botulinum Serotype A from a Pseudo-peptide Binding Mode to a Small Molecule That is Active in Primary Neurons The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17092934 Anthrax Lethal Toxin Impairs Innate Immune Functions of Alveolar Macrophages and Facilitates Bacillus Anthracis Survival Infection and Immunity. Sep, 2006 | Pubmed ID: 16926394 Passive Immunotherapy of Bacillus Anthracis Pulmonary Infection in Mice with Antisera Produced by DNA Immunization Vaccine. Jul, 2006 | Pubmed ID: 16790303 Dominance of Human Innate Immune Responses in Primary Francisella Tularensis Live Vaccine Strain Vaccination The Journal of Allergy and Clinical Immunology. May, 2006 | Pubmed ID: 16675351 Antisense Treatments for Biothreat Agents Current Opinion in Molecular Therapeutics. Apr, 2006 | Pubmed ID: 16610760 Conserved Receptor-binding Domains of Lake Victoria Marburgvirus and Zaire Ebolavirus Bind a Common Receptor The Journal of Biological Chemistry. Jun, 2006 | Pubmed ID: 16595665 VP35 Knockdown Inhibits Ebola Virus Amplification and Protects Against Lethal Infection in Mice Antimicrobial Agents and Chemotherapy. Mar, 2006 | Pubmed ID: 16495261 Gene-specific Countermeasures Against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers PLoS Pathogens. Jan, 2006 | Pubmed ID: 16415982 The Rapidly Advancing Field of Biodefense Benefits Many Other, Critical Public Health Concerns Discovery Medicine. Aug, 2005 | Pubmed ID: 20704875 Reemergence of Monkeypox: Prevalence, Diagnostics, and Countermeasures Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Dec, 2005 | Pubmed ID: 16288402 Integrated Bioassays in Microfluidic Devices: Botulinum Toxin Assays Journal of Biomolecular Screening. Dec, 2005 | Pubmed ID: 16234350 Persistence of Zinc-binding Bacterial Superantigens at the Surface of Antigen-presenting Cells Contributes to the Extreme Potency of These Superantigens As T-cell Activators Infection and Immunity. Sep, 2005 | Pubmed ID: 16113251 Anthrax Biosensor, Protective Antigen Ion Channel Asymmetric Blockade The Journal of Biological Chemistry. Oct, 2005 | Pubmed ID: 16087661 Filovirus-like Particles As Vaccines and Discovery Tools Expert Review of Vaccines. Jun, 2005 | Pubmed ID: 16026254 Induction of Humoral and CD8+ T Cell Responses Are Required for Protection Against Lethal Ebola Virus Infection Journal of Immunology (Baltimore, Md. : 1950). Jul, 2005 | Pubmed ID: 16002721 An All-atom Model of the Pore-like Structure of Hexameric VP40 from Ebola: Structural Insights into the Monomer-hexamer Transition Journal of Structural Biology. Jul, 2005 | Pubmed ID: 15908231 Analysis of Ebola Virus and VLP Release Using an Immunocapture Assay Journal of Virological Methods. Jul, 2005 | Pubmed ID: 15893559 Dendritic Cells Endocytose Bacillus Anthracis Spores: Implications for Anthrax Pathogenesis Journal of Immunology (Baltimore, Md. : 1950). May, 2005 | Pubmed ID: 15843553 Virus-like Particles Exhibit Potential As a Pan-filovirus Vaccine for Both Ebola and Marburg Viral Infections Vaccine. Apr, 2005 | Pubmed ID: 15811650 The Evolving Field of Biodefence: Therapeutic Developments and Diagnostics Nature Reviews. Drug Discovery. Apr, 2005 | Pubmed ID: 15803193 Association of Ebola Virus Matrix Protein VP40 with Microtubules Journal of Virology. Apr, 2005 | Pubmed ID: 15795257 Human Leukocyte Antigen-DQ8 Transgenic Mice: a Model to Examine the Toxicity of Aerosolized Staphylococcal Enterotoxin B Infection and Immunity. Apr, 2005 | Pubmed ID: 15784591 Lactobacilli Activate Human Dendritic Cells That Skew T Cells Toward T Helper 1 Polarization Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15710900 Purified Bacillus Anthracis Lethal Toxin Complex Formed in Vitro and During Infection Exhibits Functional and Biological Activity The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15644338 Conformational Sampling of the Botulinum Neurotoxin Serotype A Light Chain: Implications for Inhibitor Binding Bioorganic & Medicinal Chemistry. Jan, 2005 | Pubmed ID: 15598556 Marburg Virus-like Particles Protect Guinea Pigs from Lethal Marburg Virus Infection Vaccine. Sep, 2004 | Pubmed ID: 15308377 Ebola and Marburg Virus-like Particles Activate Human Myeloid Dendritic Cells Virology. Sep, 2004 | Pubmed ID: 15302213 Role of Natural Killer Cells in Innate Protection Against Lethal Ebola Virus Infection The Journal of Experimental Medicine. Jul, 2004 | Pubmed ID: 15249592 Time-lapse Confocal Imaging of Development of Bacillus Anthracis in Macrophages The Journal of Infectious Diseases. Apr, 2004 | Pubmed ID: 15031802 Generation of Marburg Virus-like Particles by Co-expression of Glycoprotein and Matrix Protein FEMS Immunology and Medical Microbiology. Jan, 2004 | Pubmed ID: 14734183 Identification of Small Molecule Inhibitors of Anthrax Lethal Factor Nature Structural & Molecular Biology. Jan, 2004 | Pubmed ID: 14718925 In Vivo Oligomerization and Raft Localization of Ebola Virus Protein VP40 During Vesicular Budding Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003 | Pubmed ID: 14673115 Ebola Virus-like Particles Protect from Lethal Ebola Virus Infection Proceedings of the National Academy of Sciences of the United States of America. Dec, 2003 | Pubmed ID: 14673108 Ebola and Marburg Viruses Replicate in Monocyte-derived Dendritic Cells Without Inducing the Production of Cytokines and Full Maturation The Journal of Infectious Diseases. Dec, 2003 | Pubmed ID: 14639532 Novel Small Molecule Inhibitors of Botulinum Neurotoxin A Metalloprotease Activity Biochemical and Biophysical Research Communications. Oct, 2003 | Pubmed ID: 14511652 Mutational Effects on Protein Folding Stability and Antigenicity: the Case of Streptococcal Pyrogenic Exotoxin A Clinical Immunology (Orlando, Fla.). Jul, 2003 | Pubmed ID: 12865072 Generation of Protective Immunity by Inactivated Recombinant Staphylococcal Enterotoxin B Vaccine in Nonhuman Primates and Identification of Correlates of Immunity Clinical Immunology (Orlando, Fla.). Jul, 2003 | Pubmed ID: 12865071 Correlation of Body Temperature with Protection Against Staphylococcal Enterotoxin B Exposure and Use in Determining Vaccine Dose-schedule Vaccine. Jun, 2003 | Pubmed ID: 12798619 Molecular Mechanisms of Filovirus Cellular Trafficking Microbes and Infection / Institut Pasteur. Jun, 2003 | Pubmed ID: 12787740 Lethal Shock Induced by Streptococcal Pyrogenic Exotoxin A in Mice Transgenic for Human Leukocyte Antigen-DQ8 and Human CD4 Receptors: Implications for Development of Vaccines and Therapeutics The Journal of Infectious Diseases. Aug, 2002 | Pubmed ID: 12195377 Humanlike Immune Response of Human Leukocyte Antigen-DR3 Transgenic Mice to Staphylococcal Enterotoxins: a Novel Model for Superantigen Vaccines The Journal of Infectious Diseases. Jun, 2002 | Pubmed ID: 12085321 Protection Against Bacterial Superantigen Staphylococcal Enterotoxin B by Passive Vaccination Infection and Immunity. May, 2002 | Pubmed ID: 11953360 Lipid Raft Microdomains: a Gateway for Compartmentalized Trafficking of Ebola and Marburg Viruses The Journal of Experimental Medicine. Mar, 2002 | Pubmed ID: 11877482 Production and Purification of a Recombinant Staphylococcal Enterotoxin B Vaccine Candidate Expressed in Escherichia Coli Protein Expression and Purification. Mar, 2002 | Pubmed ID: 11858726 Et højt indhold Imaging Assay til identifikation af botulinumneurotoksin inhibitorer Krishna P. Kota1,6, Veronica Soloveva2,6,7, Laura M. Wanner3,6, Glenn Gomba4,6, Erkan Kiris3,5,6, Rekha G. Panchal6, Christopher D. Kane2,6,7, Sina Bavari6 1Perkin Elmer Inc., 2Henry M. Jackson Foundation, 3The Geneva Foundation, 4ORISE, 5Frederick National Laboratory for Cancer Research, 6Division of Molecular and Translational Sciences, US Army Medical Research Institute of Infectious Diseases, 7DoD Biotechnology High Performance Computing Software Applications Institute (BHSAI), Telemedicine and Advanced Technology Research Center (TATRC), US Army Medical Research and Materiel Command (USAMRMC) 신경과학
Et højt indhold Imaging Assay til identifikation af botulinumneurotoksin inhibitorer Krishna P. Kota1,6, Veronica Soloveva2,6,7, Laura M. Wanner3,6, Glenn Gomba4,6, Erkan Kiris3,5,6, Rekha G. Panchal6, Christopher D. Kane2,6,7, Sina Bavari6 1Perkin Elmer Inc., 2Henry M. Jackson Foundation, 3The Geneva Foundation, 4ORISE, 5Frederick National Laboratory for Cancer Research, 6Division of Molecular and Translational Sciences, US Army Medical Research Institute of Infectious Diseases, 7DoD Biotechnology High Performance Computing Software Applications Institute (BHSAI), Telemedicine and Advanced Technology Research Center (TATRC), US Army Medical Research and Materiel Command (USAMRMC) 신경과학