Nicholas Fletcher Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology The University of Queensland Biography Publications Institution JoVE Articles Nicholas Fletcher has not added a biography. If you are Nicholas Fletcher and would like to personalize this page please email our Author Liaison for assistance. Publications Investigation of a Dual SiRNA/Chemotherapy Delivery System for Breast Cancer Therapy ACS Omega. May, 2022 | Pubmed ID: 35647423 Antibody-Based Formats to Target Glioblastoma: Overcoming Barriers to Protein Drug Delivery Molecular Pharmaceutics. 05, 2022 | Pubmed ID: 35438509 Nanoparticle Based Medicines: Approaches for Evading and Manipulating the Mononuclear Phagocyte System and Potential for Clinical Translation Biomaterials Science. Jun, 2022 | Pubmed ID: 35419582 Understanding Nanomedicine Treatment in an Aggressive Spontaneous Brain Cancer Model at the Stage of Early Blood Brain Barrier Disruption Biomaterials. 04, 2022 | Pubmed ID: 35217483 Clinical Development of an Anti-GPC-1 Antibody for the Treatment of Cancer Expert Opinion on Biological Therapy. 05, 2022 | Pubmed ID: 35067148 Fluorophore Selection and Incorporation Contribute to Permeation and Distribution Behaviors of Hyperbranched Polymers in Multi-Cellular Tumor Spheroids and Xenograft Tumor Models ACS Applied Bio Materials. 03, 2021 | Pubmed ID: 35014306 Evaluation of the in Vivo Fate of Ultrapure Alginate in a BALB/c Mouse Model Carbohydrate Polymers. Jun, 2021 | Pubmed ID: 33838824 Engineering Fluorescent Gold Nanoclusters Using Xanthate-Functionalized Hydrophilic Polymers: Toward Enhanced Monodispersity and Stability Nano Letters. 01, 2021 | Pubmed ID: 33350838 Understanding the Role of Colon-specific Microparticles Based on Retrograded Starch/pectin in the Delivery of Chitosan Nanoparticles Along the Gastrointestinal Tract European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Jan, 2021 | Pubmed ID: 33309846 Targeted and Modular Architectural Polymers Employing Bioorthogonal Chemistry for Quantitative Therapeutic Delivery Chemical Science. Mar, 2020 | Pubmed ID: 34122834 Characterization of the Biodistribution of a Silica Vesicle Nanovaccine Carrying a Protective Antigen With Live Animal Imaging Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 33537291 The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats Nanomaterials (Basel, Switzerland). Dec, 2020 | Pubmed ID: 33302413 Controlling the Biological Fate of Micellar Nanoparticles: Balancing Stealth and Targeting ACS Nano. 10, 2020 | Pubmed ID: 32936613 Effect of Chain-End Chemistries on the Efficiency of Coupling Antibodies to Polymers Using Unnatural Amino Acids Macromolecular Rapid Communications. Nov, 2020 | Pubmed ID: 32935886 Next-Generation Polymeric Nanomedicines for Oncology: Perspectives and Future Directions Macromolecular Rapid Communications. Sep, 2020 | Pubmed ID: 32767396 Hyperbranched Poly(2-oxazoline)s and Poly(ethylene Glycol): A Structure-Activity Comparison of Biodistribution Biomacromolecules. 08, 2020 | Pubmed ID: 32687312 Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies ACS Central Science. May, 2020 | Pubmed ID: 32490189 Direct Comparison of Poly(ethylene Glycol) and Phosphorylcholine Drug-Loaded Nanoparticles In Vitro and In Vivo Biomacromolecules. 06, 2020 | Pubmed ID: 32343128 Polymer Design and Component Selection Contribute to Uptake, Distribution & Trafficking Behaviours of Polyethylene Glycol Hyperbranched Polymers in Live MDA-MB-468 Breast Cancer Cells Biomaterials Science. Nov, 2019 | Pubmed ID: 31469127 Modulating Targeting of Poly(ethylene Glycol) Particles to Tumor Cells Using Bispecific Antibodies Advanced Healthcare Materials. 05, 2019 | Pubmed ID: 30868751 Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma Frontiers in Medicine. 2019 | Pubmed ID: 30809524 Ultrasound-responsive Nanobubbles for Enhanced Intravitreal Drug Migration: An Ex Vivo Evaluation European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Mar, 2019 | Pubmed ID: 30660691 Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility ACS Central Science. Jun, 2018 | Pubmed ID: 29974067 Gold Nanocluster-Mediated Cellular Death Under Electromagnetic Radiation ACS Applied Materials & Interfaces. Nov, 2017 | Pubmed ID: 29116739 Localised Delivery of Doxorubicin to Prostate Cancer Cells Through a PSMA-targeted Hyperbranched Polymer Theranostic Biomaterials. Oct, 2017 | Pubmed ID: 28711780 Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies Advanced Healthcare Materials. 08, 2016 | Pubmed ID: 27283923 Targeting Nanomedicines to Prostate Cancer: Evaluation of Specificity of Ligands to Two Different Receptors In Vivo Pharmaceutical Research. 10, 2016 | Pubmed ID: 27225496 Bioproduction of Highly Charged Designer Peptide Surfactants Via a Chemically Cleavable Coiled-coil Heteroconcatemer Biotechnology and Bioengineering. Feb, 2015 | Pubmed ID: 25212732 Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells Malcolm Lim1, Nicholas Fletcher2, Amy McCart Reed1, Melanie Flint3, Kristofer Thurecht2, Jodi Saunus*1,4, Sunil R. Lakhani*1,5 1UQ Centre for Clinical Research, The University of Queensland, 2Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, 3School of Biomedical Sciences, The University of Queensland, 4Mater Research and Mater Research Institute, The University of Queensland, 5Pathology Queensland, Royal Brisbane Women's Hospital JoVE 64216 암 연구학
Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells Malcolm Lim1, Nicholas Fletcher2, Amy McCart Reed1, Melanie Flint3, Kristofer Thurecht2, Jodi Saunus*1,4, Sunil R. Lakhani*1,5 1UQ Centre for Clinical Research, The University of Queensland, 2Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, 3School of Biomedical Sciences, The University of Queensland, 4Mater Research and Mater Research Institute, The University of Queensland, 5Pathology Queensland, Royal Brisbane Women's Hospital JoVE 64216 암 연구학