M. Lienhard Schmitz

Publications

• The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice
  Biomedicines. Mar, 2018  |   Pubmed ID: 29562713
• NF-κB P65 Serine 467 Phosphorylation Sensitizes Mice to Weight Gain and TNFα-or Diet-induced Inflammation
  Biochimica Et Biophysica Acta. 10, 2017  |   Pubmed ID: 28723419
• The CCR4-NOT Complex Contributes to Repression of Major Histocompatibility Complex Class II Transcription
  Scientific Reports. Jun, 2017  |   Pubmed ID: 28615693
• The NF-κB-dependent and -independent Transcriptome and Chromatin Landscapes of Human Coronavirus 229E-infected Cells
  PLoS Pathogens. Mar, 2017  |   Pubmed ID: 28355270
• Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 27761830
• The Influenza A Virus Genotype Determines the Antiviral Function of NF-κB
  Journal of Virology. 09, 2016  |   Pubmed ID: 27356900
• K63-Ubiquitylation and TRAF6 Pathways Regulate Mammalian P-Body Formation and MRNA Decapping
  Molecular Cell. 06, 2016  |   Pubmed ID: 27315556
• SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies
  Scientific Reports. 05, 2016  |   Pubmed ID: 27211601
• HIPK Family Kinases Bind and Regulate the Function of the CCR4-NOT Complex
  Molecular Biology of the Cell. 06, 2016  |   Pubmed ID: 27122605
• Cyclin-Dependent Kinases As Coregulators of Inflammatory Gene Expression
  Trends in Pharmacological Sciences. Feb, 2016  |   Pubmed ID: 26719217
• The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB P65
  Cell Reports. Feb, 2015  |   Pubmed ID: 25660023
• SUMO Modification of TBK1 at the Adaptor-binding C-terminal Coiled-coil Domain Contributes to Its Antiviral Activity
  Biochimica Et Biophysica Acta. Jan, 2015  |   Pubmed ID: 25409927
• The Intricate Interplay Between RNA Viruses and NF-κB
  Biochimica Et Biophysica Acta. Nov, 2014  |   Pubmed ID: 25116307
• Expression Pattern of Protease Activated Receptors in Lymphoid Cells
  Cellular Immunology. Mar-Apr, 2014  |   Pubmed ID: 24637088
• Cyclin-dependent Kinase 6 is a Chromatin-bound Cofactor for NF-κB-dependent Gene Expression
  Molecular Cell. Jan, 2014  |   Pubmed ID: 24389100
• The Cytokine-induced Conformational Switch of Nuclear Factor κB P65 is Mediated by P65 Phosphorylation
  The Biochemical Journal. Feb, 2014  |   Pubmed ID: 24175631
• Hsc70 is a Novel Interactor of NF-kappaB P65 in Living Hippocampal Neurons
  PloS One. 2013  |   Pubmed ID: 23762333
• Homeodomain-interacting Protein Kinase 2-dependent Repression of Myogenic Differentiation is Relieved by Its Caspase-mediated Cleavage
  Nucleic Acids Research. Jun, 2013  |   Pubmed ID: 23620283
• Posttranslational Modifications Regulate HIPK2, a Driver of Proliferative Diseases
  Journal of Molecular Medicine (Berlin, Germany). Sep, 2013  |   Pubmed ID: 23616089
• HIPK2 Kinase Activity Depends on Cis-autophosphorylation of Its Activation Loop
  Journal of Molecular Cell Biology. Feb, 2013  |   Pubmed ID: 23000554
• Cyclin-dependent Kinase 6 Phosphorylates NF-κB P65 at Serine 536 and Contributes to the Regulation of Inflammatory Gene Expression
  PloS One. 2012  |   Pubmed ID: 23300567
• Regulation of the Tumor Suppressor PML by Sequential Post-translational Modifications
  Frontiers in Oncology. 2012  |   Pubmed ID: 23293771
• The Coactivator Role of Histone Deacetylase 3 in IL-1-signaling Involves Deacetylation of P65 NF-κB
  Nucleic Acids Research. Oct, 2012  |   Pubmed ID: 23087373
• SIAH-mediated Ubiquitination and Degradation of Acetyl-transferases Regulate the P53 Response and Protein Acetylation
  Biochimica Et Biophysica Acta. Dec, 2012  |   Pubmed ID: 23044042
• A Redox-regulated SUMO/acetylation Switch of HIPK2 Controls the Survival Threshold to Oxidative Stress
  Molecular Cell. May, 2012  |   Pubmed ID: 22503103
• Regulation of NF-κB Activity by Competition Between RelA Acetylation and Ubiquitination
  Oncogene. Feb, 2012  |   Pubmed ID: 21706061
• Signal Integration, Crosstalk Mechanisms and Networks in the Function of Inflammatory Cytokines
  Biochimica Et Biophysica Acta. Dec, 2011  |   Pubmed ID: 21787809
• Control of Nuclear HIPK2 Localization and Function by a SUMO Interaction Motif
  Biochimica Et Biophysica Acta. Feb, 2011  |   Pubmed ID: 21145359
• Specification of the NF-kappaB Transcriptional Response by P65 Phosphorylation and TNF-induced Nuclear Translocation of IKK Epsilon
  Nucleic Acids Research. Oct, 2010  |   Pubmed ID: 20507904
• SUMOylation-dependent Localization of IKKepsilon in PML Nuclear Bodies is Essential for Protection Against DNA-damage-triggered Cell Death
  Molecular Cell. Feb, 2010  |   Pubmed ID: 20188669
• Activation of T Cells: Releasing the Brakes by Proteolytic Elimination of Cbl-b
  Science Signaling. Jun, 2009  |   Pubmed ID: 19549983
• Autoregulatory Feedback Loops Terminating the NF-kappaB Response
  Trends in Biochemical Sciences. Mar, 2009  |   Pubmed ID: 19233657
• An Inducible Autoregulatory Loop Between HIPK2 and Siah2 at the Apex of the Hypoxic Response
  Nature Cell Biology. Jan, 2009  |   Pubmed ID: 19043406
• Functional Architecture of the Cell Nucleus
  Biochimica Et Biophysica Acta. Nov, 2008  |   Pubmed ID: 18929934
• A Bacterial Small Molecule Undermining Immune Response Signaling
  Chembiochem : a European Journal of Chemical Biology. Nov, 2008  |   Pubmed ID: 18823058
• NIK and Cot Cooperate to Trigger NF-kappaB P65 Phosphorylation
  Biochemical and Biophysical Research Communications. Jun, 2008  |   Pubmed ID: 18439422
• NF-kappaB Inhibitors for the Treatment of Inflammatory Diseases and Cancer
  Current Medicinal Chemistry. 2007  |   Pubmed ID: 17305539
• HIPK2: a Versatile Switchboard Regulating the Transcription Machinery and Cell Death
  Cell Cycle (Georgetown, Tex.). Jan, 2007  |   Pubmed ID: 17245128
• Phosphorylation-dependent Control of Pc2 SUMO E3 Ligase Activity by Its Substrate Protein HIPK2
  Molecular Cell. Oct, 2006  |   Pubmed ID: 17018294
• Roles of HIPK1 and HIPK2 in AML1- and P300-dependent Transcription, Hematopoiesis and Blood Vessel Formation
  The EMBO Journal. Sep, 2006  |   Pubmed ID: 16917507
• Autoregulatory Control of the P53 Response by Caspase-mediated Processing of HIPK2
  The EMBO Journal. May, 2006  |   Pubmed ID: 16601678
• Controlling NF-kappaB Activation in T Cells by Costimulatory Receptors
  Cell Death and Differentiation. May, 2006  |   Pubmed ID: 16410801