Alexander F. Schier Department of Molecular and Cellular Biology Harvard University Biography Publications Institution JoVE Articles Alexander F. Schier has not added a biography. If you are Alexander F. Schier and would like to personalize this page please email our Author Liaison for assistance. Publications The Study of Psychiatric Disease Genes and Drugs in Zebrafish Current Opinion in Neurobiology. Feb, 2015 | Pubmed ID: 25523356 Identifying (non-)coding RNAs and Small Peptides: Challenges and Opportunities BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Jan, 2015 | Pubmed ID: 25345765 High-resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies Cell. Dec, 2014 | Pubmed ID: 25497548 Obituary: Walter J. Gehring (1939-2014) Development (Cambridge, England). Sep, 2014 | Pubmed ID: 25085977 Neuropeptidergic Control of Sleep and Wakefulness Annual Review of Neuroscience. 2014 | Pubmed ID: 25032501 Efficient Mutagenesis by Cas9 Protein-mediated Oligonucleotide Insertion and Large-scale Assessment of Single-guide RNAs PloS One. 2014 | Pubmed ID: 24873830 Neuropeptidergic Signaling Partitions Arousal Behaviors in Zebrafish The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2014 | Pubmed ID: 24573274 Toddler: an Embryonic Signal That Promotes Cell Movement Via Apelin Receptors Science (New York, N.Y.). Feb, 2014 | Pubmed ID: 24407481 Canonical Nucleosome Organization at Promoters Forms During Genome Activation Genome Research. Feb, 2014 | Pubmed ID: 24285721 Should I Stay or Should I Go: Neuromodulators of Behavioral States Cell. Aug, 2013 | Pubmed ID: 23993087 Zebrabow: Multispectral Cell Labeling for Cell Tracing and Lineage Analysis in Zebrafish Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23757414 Sites of Action of Sleep and Wake Drugs: Insights from Model Organisms Current Opinion in Neurobiology. Oct, 2013 | Pubmed ID: 23706898 Ribosome Profiling Reveals Resemblance Between Long Non-coding RNAs and 5' Leaders of Coding RNAs Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23698349 Specified Neural Progenitors Sort to Form Sharp Domains After Noisy Shh Signaling Cell. Apr, 2013 | Pubmed ID: 23622240 Genomics: Zebrafish Earns Its Stripes Nature. Apr, 2013 | Pubmed ID: 23594741 Morphogen Transport Development (Cambridge, England). Apr, 2013 | Pubmed ID: 23533171 Optical Control of Metabotropic Glutamate Receptors Nature Neuroscience. Apr, 2013 | Pubmed ID: 23455609 A Large-scale Zebrafish Gene Knockout Resource for the Genome-wide Study of Gene Function Genome Research. Apr, 2013 | Pubmed ID: 23382537 The Tangential Nucleus Controls a Gravito-inertial Vestibulo-ocular Reflex Current Biology : CB. Jun, 2012 | Pubmed ID: 22704987 Attenuation of Notch and Hedgehog Signaling is Required for Fate Specification in the Spinal Cord PLoS Genetics. 2012 | Pubmed ID: 22685423 Brain-wide Neuronal Dynamics During Motor Adaptation in Zebrafish Nature. May, 2012 | Pubmed ID: 22622571 CCDC103 Mutations Cause Primary Ciliary Dyskinesia by Disrupting Assembly of Ciliary Dynein Arms Nature Genetics. Jun, 2012 | Pubmed ID: 22581229 Bivalent Histone Modifications in Early Embryogenesis Current Opinion in Cell Biology. Jun, 2012 | Pubmed ID: 22513113 Differential Diffusivity of Nodal and Lefty Underlies a Reaction-diffusion Patterning System Science (New York, N.Y.). May, 2012 | Pubmed ID: 22499809 Touch Responsiveness in Zebrafish Requires Voltage-gated Calcium Channel 2.1b Journal of Neurophysiology. Jul, 2012 | Pubmed ID: 22490555 The Role of Hair Cells, Cilia and Ciliary Motility in Otolith Formation in the Zebrafish Otic Vesicle Development (Cambridge, England). May, 2012 | Pubmed ID: 22461562 Nanog-like Regulates Endoderm Formation Through the Mxtx2-Nodal Pathway Developmental Cell. Mar, 2012 | Pubmed ID: 22421047 BAPTI and BAPTISM Birthdating of Neurons in Zebrafish Cold Spring Harbor Protocols. Jan, 2012 | Pubmed ID: 22194263 Robo2 Determines Subtype-specific Axonal Projections of Trigeminal Sensory Neurons Development (Cambridge, England). Feb, 2012 | Pubmed ID: 22190641 Systematic Identification of Long Noncoding RNAs Expressed During Zebrafish Embryogenesis Genome Research. Mar, 2012 | Pubmed ID: 22110045 Morphogen Gradients: from Generation to Interpretation Annual Review of Cell and Developmental Biology. 2011 | Pubmed ID: 21801015 Extracellular Movement of Signaling Molecules Developmental Cell. Jul, 2011 | Pubmed ID: 21763615 行動ゼブラフィッシュ神経作用薬のスクリーニングします。 Developmental Neurobiology. May, 2011 | Pubmed ID: 21567979 Non-coding RNAs As Regulators of Embryogenesis Nature Reviews. Genetics. Feb, 2011 | Pubmed ID: 21245830 Multicolor Brainbow Imaging in Zebrafish Cold Spring Harbor Protocols. Jan, 2011 | Pubmed ID: 21205846 睡眠と覚醒ゼブラフィッシュを監視します。 Methods in Cell Biology. 2010 | Pubmed ID: 21111222 Chromatin Signature of Embryonic Pluripotency is Established During Genome Activation Nature. Apr, 2010 | Pubmed ID: 20336069 Monitoring Neural Activity with Bioluminescence During Natural Behavior Nature Neuroscience. Apr, 2010 | Pubmed ID: 20305645 No Tail Integrates Two Modes of Mesoderm Induction Development (Cambridge, England). Apr, 2010 | Pubmed ID: 20215349 ゼブラフィッシュの行動プロファイル薬の生物的ターゲットと残りの部分/覚醒へのリンクします。 Science (New York, N.Y.). Jan, 2010 | Pubmed ID: 20075256 Nodal Morphogens Cold Spring Harbor Perspectives in Biology. Nov, 2009 | Pubmed ID: 20066122 Developmental Biology: Rise of the Source-sink Model Nature. Sep, 2009 | Pubmed ID: 19779439 Dampened Hedgehog Signaling but Normal Wnt Signaling in Zebrafish Without Cilia Development (Cambridge, England). Sep, 2009 | Pubmed ID: 19700616 Nodal Signaling Promotes the Speed and Directional Movement of Cardiomyocytes in Zebrafish Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2008 | Pubmed ID: 18985714 ゼブラフィッシュ TRPA1 チャネルが必要な行動のためではなく、thermosensation または機械刺激受容の有毛細胞機能。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2008 | Pubmed ID: 18829968 In Vivo Birthdating by BAPTISM Reveals That Trigeminal Sensory Neuron Diversity Depends on Early Neurogenesis Development (Cambridge, England). Oct, 2008 | Pubmed ID: 18755773 Escape Behavior Elicited by Single, Channelrhodopsin-2-evoked Spikes in Zebrafish Somatosensory Neurons Current Biology : CB. Aug, 2008 | Pubmed ID: 18682213 Targeted Mutagenesis in Zebrafish Nature Biotechnology. Jun, 2008 | Pubmed ID: 18536686 Clearing the Path for Germ Cells Cell. Feb, 2008 | Pubmed ID: 18267065 Members of the MiRNA-200 Family Regulate Olfactory Neurogenesis Neuron. Jan, 2008 | Pubmed ID: 18184563 Maternal Nodal and Zebrafish Embryogenesis Nature. Nov, 2007 | Pubmed ID: 17994032 Target Protectors Reveal Dampening and Balancing of Nodal Agonist and Antagonist by MiR-430 Science (New York, N.Y.). Oct, 2007 | Pubmed ID: 17761850 The Maternal-zygotic Transition: Death and Birth of RNAs Science (New York, N.Y.). Apr, 2007 | Pubmed ID: 17446392 Nodal Signaling Activates Differentiation Genes During Zebrafish Gastrulation Developmental Biology. Apr, 2007 | Pubmed ID: 17306247 オレキシン/ヒポクレチンの過剰発現は、不眠症のような表現型ゼブラフィッシュを誘導します。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2006 | Pubmed ID: 17182791 Differential Regulation of Germline MRNAs in Soma and Germ Cells by Zebrafish MiR-430 Current Biology : CB. Nov, 2006 | Pubmed ID: 17084698 Polycystin 2 タバコプロトプ、ゼブラフィッシュの関数。 Journal of the American Society of Nephrology : JASN. Oct, 2006 | Pubmed ID: 16943304 ゼブラフィッシュ ミール 430 Deadenylation と母性 Mrna のクリアランスを促進します。 Science (New York, N.Y.). Apr, 2006 | Pubmed ID: 16484454 神経胚形成の間にカップルの細胞分裂と形態形成のシグナリング平面内細胞極性 Nature. Jan, 2006 | Pubmed ID: 16407953 Axis Formation: Squint Comes into Focus Current Biology : CB. Dec, 2005 | Pubmed ID: 16360671 Molecular Genetics of Axis Formation in Zebrafish Annual Review of Genetics. 2005 | Pubmed ID: 16285872 Assembly of Trigeminal Sensory Ganglia by Chemokine Signaling Neuron. Sep, 2005 | Pubmed ID: 16129396 斥力相互作用形態とゼブラフィッシュ末梢感覚アーバーの機能構成を形作る Current Biology : CB. May, 2005 | Pubmed ID: 15886097 繊毛駆動型流体の流れのゼブラフィッシュ切り口、脳クッパーの小胞の正常の器官形成が必要です。 Development (Cambridge, England). Apr, 2005 | Pubmed ID: 15790966 MicroRNAs Regulate Brain Morphogenesis in Zebrafish Science (New York, N.Y.). May, 2005 | Pubmed ID: 15774722 Nodal Stability Determines Signaling Range Current Biology : CB. Jan, 2005 | Pubmed ID: 15649361 Zebrafish Gli3 Functions As Both an Activator and a Repressor in Hedgehog Signaling Developmental Biology. Jan, 2005 | Pubmed ID: 15617692 Lefty Blocks a Subset of TGFbeta Signals by Antagonizing EGF-CFC Coreceptors PLoS Biology. Feb, 2004 | Pubmed ID: 14966532 Developmental Biology: Tail of Decay Nature. Jan, 2004 | Pubmed ID: 14749811 Nodal Signaling in Vertebrate Development Annual Review of Cell and Developmental Biology. 2003 | Pubmed ID: 14570583 Mixer/Bon and FoxH1/Sur Have Overlapping and Divergent Roles in Nodal Signaling and Mesendoderm Induction Development (Cambridge, England). Dec, 2003 | Pubmed ID: 14522874 The Role of the Zebrafish Nodal-related Genes Squint and Cyclops in Patterning of Mesendoderm Development (Cambridge, England). May, 2003 | Pubmed ID: 12642489 Genetic Analysis of Zebrafish Gli1 and Gli2 Reveals Divergent Requirements for Gli Genes in Vertebrate Development Development (Cambridge, England). Apr, 2003 | Pubmed ID: 12620981 Chemokine Signaling: Rules of Attraction Current Biology : CB. Mar, 2003 | Pubmed ID: 12620211 EGF-CFC Proteins Are Essential Coreceptors for the TGF-beta Signals Vg1 and GDF1 Genes & Development. Jan, 2003 | Pubmed ID: 12514096 Lefty Proteins Are Long-range Inhibitors of Squint-mediated Nodal Signaling Current Biology : CB. Dec, 2002 | Pubmed ID: 12498687 Production of Maternal-zygotic Mutant Zebrafish by Germ-line Replacement Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002 | Pubmed ID: 12397179 Mesoderm Induction and Patterning Results and Problems in Cell Differentiation. 2002 | Pubmed ID: 12353475 A Novel Microtubule Destabilizing Entity from Orthogonal Synthesis of Triazine Library and Zebrafish Embryo Screening Journal of the American Chemical Society. Oct, 2002 | Pubmed ID: 12296721 A Loss-of-function Mutation in the CFC Domain of TDGF1 is Associated with Human Forebrain Defects Human Genetics. May, 2002 | Pubmed ID: 12073012 ゼブラフィッシュ原腸陥入時の Stat3 コントロール細胞運動。 Developmental Cell. Mar, 2002 | Pubmed ID: 11879641 光変換後の蛍光減衰を使用して生活ゼブラフィッシュ胚におけるタンパク質の安定性の測定(FDAP) Katherine W. Rogers1, Alexander Bläßle2, Alexander F. Schier1, Patrick Müller2 1Department of Molecular and Cellular Biology, Harvard University, 2Systems Biology of Development Group, Friedrich Miescher Laboratory of the Max Planck Society JoVE 52266 발생학
光変換後の蛍光減衰を使用して生活ゼブラフィッシュ胚におけるタンパク質の安定性の測定(FDAP) Katherine W. Rogers1, Alexander Bläßle2, Alexander F. Schier1, Patrick Müller2 1Department of Molecular and Cellular Biology, Harvard University, 2Systems Biology of Development Group, Friedrich Miescher Laboratory of the Max Planck Society JoVE 52266 발생학