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Rapid Determination of Antibody-Antigen Affinity by Mass Photometry
JoVE Journal
Biochemistry
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JoVE Journal Biochemistry
Rapid Determination of Antibody-Antigen Affinity by Mass Photometry

Rapid Determination of Antibody-Antigen Affinity by Mass Photometry

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10:17 min

February 08, 2021

DOI:

10:17 min
February 08, 2021

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Summary

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We describe a single-molecule approach to antigen-antibody affinity measurements using mass photometry (MP). The MP-based protocol is fast, accurate, uses a very small amount of material, and does not require protein modification.

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