Here, we describe an easy-to-implement, standardized, microphysiological system that reflects the complexity of the human bone marrow's in vivo structure, providing a pertinent model to finely study a broad range of normal and pathological events.
Arizkane, K., Geistlich, K., Moindrot, L., Risson, E., Jeanpierre, S., Barral, L., Bobard, A., Menegazzi, G., Voeltzel, T., Maguer-Satta, V., Lefort, S. A Human Bone Marrow 3D Model to Investigate the Dynamics and Interactions Between Resident Cells in Physiological or Tumoral Contexts. J. Vis. Exp. (190), e64736, doi:10.3791/64736 (2022).