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In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells
JoVE Journal
発生生物学
This content is Free Access.
JoVE Journal 発生生物学
In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells

In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells

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06:01 min

December 03, 2020

DOI:

06:01 min
December 03, 2020

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概要

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Here we provide a protocol to generate in vitro NMJs from human induced pluripotent stem cells (iPSCs). This method can induce NMJs with mature morphology and function in 1 month in a single well. The resulting NMJs could potentially be used to model related diseases, to study pathological mechanisms or to screen drug compounds for therapy.

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