ジャーナル
/
生化学
/
Identification of Functional Protein Regions Through Chimeric Protein Construction
JoVE Journal
生化学
このコンテンツを視聴するには、JoVE 購読が必要です。  サインイン又は無料トライアルを申し込む。
JoVE Journal 生化学
Identification of Functional Protein Regions Through Chimeric Protein Construction

Identification of Functional Protein Regions Through Chimeric Protein Construction

10,178 Views

•

11:39 min

•

January 08, 2019

DOI:

10.3791/58786-v

DOI:
10.3791/58786-v

•

11:39 min
January 08, 2019

•

9 Views
, , ,
1Department of Cardiac Development and Remodelling,Max Planck Institute for Heart and Lung Research, 2Partner site Rhein-Main,German Centre for Cardiovascular Research (DZHK)

概要

Automatically generated

Structurally related proteins frequently exert distinct biological functions. The exchange of equivalent regions of these proteins in order to create chimeric proteins constitutes an innovative approach to identify critical protein regions that are responsible for their functional divergence.

Explore More Videos

Protein ChimeraFunctional Protein RegionsProtein StructureProtein SequenceProtein Engineering分子生物学Structural BiologyProtein Domain ExchangeProtein Domain Swapping

Read Article

Cite this Article

Adrian-Segarra, J. M., Lörchner, H., Braun, T., Pöling, J. Identification of Functional Protein Regions Through Chimeric Protein Construction. J. Vis. Exp. (143), e58786, doi:10.3791/58786 (2019).

Download .ris file

Copy

Share Video

.

Copy