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章
- 00:04標題
- 00:39Preparation of the MEA/Custom Chamber Assembly
- 01:15Preparation of the Recording Bench
- 02:52Preparation of the MEA Set-up
- 04:39MEA Live Mapping
- 06:33Recording and Electrical Modulation of the Epileptiform Activity
- 08:49Results: Representative Experiment of Electrical Modulation of Ictogenesis Using Brain Slices Coupled to MEAs
- 09:21Conclusion
We illustrate how to perform recording and electrical modulation of 4-aminopyridine-induced epileptiform activity in rodent brain slices using microelectrode arrays. A custom recording chamber maintains tissue viability throughout prolonged experimental sessions. Live electrode mapping and selection of stimulating pairs are performed by a custom graphical user interface.
