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HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
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JoVE Journal 神経科学
HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

DOI:
10.3791/53717-v

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07:30 min

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July 09, 2016

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, ,
1精神医学科,Icahn School of Medicine at Mount Sinai, 2Department of Neurology,Icahn School of Medicine at Mount Sinai, 3Friedman Brain Institute,Icahn School of Medicine at Mount Sinai, 4Department of Physiology and Biophysics,Virginia Commonwealth University Medical School

章

  • 00:05標題
  • 00:56Stereotaxic Surgery to Introduce HSV Chimeric Constructs
  • 03:32Head Twitch Response Experiment
  • 05:04Data Review
  • 05:33結果
  • 06:35Conclusion

概要

自動翻訳

自動翻訳

This article describes how to inject viral vectors into the mouse frontal cortex to test behavioral assays that require GPCR heteromeric formation.

タグ

HSVTransgene ExpressionGPCR HeteromersMouse ModelBehavioral PhenotypesSerotonin 2aMetabotropic Glutamate Receptor 2Stereotactic SurgeryVirus-mediated Gene TransferAnesthesiaInjectionFrontal Cortex

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