Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

Robert J. Wickham; Jinwoo Park; Eric J. Nunes; Nii A. Addy

doi:10.3791/52468

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Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

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行動学

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JoVE Journal 行動学

Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

12,551 Views

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10:44 min

•

August 12, 2015

DOI:

10.3791/52468-v

DOI:

10.3791/52468-v

•

10:44 min

August 12, 2015

•

2 Views

Robert J. Wickham¹, Jinwoo Park², Eric J. Nunes³, Nii A. Addy^1,3,4

¹Interdepartmental Neuroscience Program,Yale University, ²Department of Biotechnical and Clinical Laboratory Sciences, School of Medicine and Biomedical Sciences,University at Buffalo, ³精神医学科,Yale School of Medicine, ⁴Department of Cellular and Molecular Physiology,Yale School of Medicine

概要

Rapid fluctuations in extracellular dopamine (DA) mediate both reward processing and motivated behavior in mammals. This manuscript describes the combined use of fast scan cyclic voltammetry (FSCV) and intra-oral tastant administration to determine how tastants alter rapid dopamine release in awake, freely moving rats.

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Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

概要

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