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Behavior

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JoVE Journal Behavior
Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats
 

Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats

Article DOI: 10.3791/52468-v • 10:45 min • August 12th, 2015
August 12th, 2015 •
1, 2, 3, 1,3,4
1Interdepartmental Neuroscience Program, Yale University, 2Department of Biotechnical and Clinical Laboratory Sciences, School of Medicine and Biomedical Sciences, University at Buffalo, 3Department of Psychiatry, Yale School of Medicine, 4Department of Cellular and Molecular Physiology, Yale School of Medicine

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Summary
Automatic Translation

Rapid fluctuations in extracellular dopamine (DA) mediate both reward processing and motivated behavior in mammals. This manuscript describes the combined use of fast scan cyclic voltammetry (FSCV) and intra-oral tastant administration to determine how tastants alter rapid dopamine release in awake, freely moving rats.

Tags

Rapid Dopamine Dynamics Fast Scan Cyclic Voltammetry Intra-oral Tastant Administration Awake Rats Phasic Dopamine Release Reward Processing Reinforcement Learning Motivational Control Electrochemical Technique Spatial Resolution Temporal Resolution In Vitro Experiments In Vivo Experiments Anesthetized Rodents Dopamine Release Mechanisms Dopamine Uptake Mechanisms Disease Models Awake Freely Moving Rodents Reward Processing Mechanisms Reward Learning Mechanisms Combined Behavior And Voltammetry Experiments Primary Rewarding Stimuli Aversive Stimuli Motor Behaviors
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