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Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
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JoVE Journal 免疫学と感染
Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes

9,741 Views

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14:05 min

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September 19, 2013

DOI:

10.3791/51043-v

DOI:
10.3791/51043-v

•

14:05 min
September 19, 2013

•

1 Views
, , , , , ,
1Unité des Interactions Bactéries Cellules,Pasteur Institute, 2INSERM U604, 3Institut National de la Recherche Agronomique (INRA), USC2020, 4Institute of Biochemistry,ETH Zürich, 5Focal Area Infection Biology, Biozentrum,University of Basel

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Listeria monocytogenes is a Gram positive bacterial pathogen frequently used as a major model for the study of intracellular parasitism. Imaging late L. monocytogenes infection stages within the context of small-interfering RNA screens allows for the global study of cellular pathways required for bacterial infection of target host cells.

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Cite this Article

Kühbacher, A., Gouin, E., Mercer, J., Emmenlauer, M., Dehio, C., Cossart, P., Pizarro-Cerdá, J. Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes. J. Vis. Exp. (79), e51043, doi:10.3791/51043 (2013).

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