Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / A Scalable Model to Study the Effects of…
JoVE Journal
Neuroscience

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Neuroscience
A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish
 

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

Article DOI: 10.3791/62709-v • 08:13 min • May 31st, 2021
May 31st, 2021 •
1,2,3, 1,2,3, 2,3, 1,2,3
1Department of Biological Sciences, University of Notre Dame, 2Center for Zebrafish Research, University of Notre Dame, 3Center for Stem Cells and Regenerative Medicine, University of Notre Dame

Capitoli

Riepilogo
Automatic Translation

We modified the Marmarou weight drop model for adult zebrafish to examine a breadth of pathologies following blunt-force traumatic brain injury (TBI) and the mechanisms underlying subsequent neuronal regeneration. This blunt-force TBI model is scalable, induces a mild, moderate, or severe TBI, and recapitulates injury heterogeneity observed in human TBI.

Tags

Scalable Model Study Effects Blunt-force Injury Adult Zebrafish Protocol Traumatic Brain Injury Characteristics Humans Procedure Mr. James Hentig Ms. Kaylee Cloghessy Doctoral Students Laboratory Petri Dish Modeling Clay Raised Platform Forceps Razor Blade Channel Fish Body Head Exposed Support Rotation Recoil Dropped Weight Mini Hole Punch Steel Disc
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter