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Cibler les agrégats alpha synuclein dans les fibres nerveuses périphériques cutanées par l'évaluation de l'immunofluorescence flottante
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JoVE Journal Neuroscienze
Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
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Cibler les agrégats alpha synuclein dans les fibres nerveuses périphériques cutanées par l'évaluation de l'immunofluorescence flottante

7,962 Views

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08:33 min

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June 25, 2019

DOI:

10.3791/59558-v

DOI:
10.3791/59558-v

•

08:33 min
June 25, 2019

•

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1Laboratory for Biomedical Neurosciences,Neurocenter of Southern Switzerland, 2Neurology Department,Neurocenter of Southern Switzerland, 3Department of Neurology, Inselspital, Bern University Hospital,University of Bern, 4Faculty of Biomedical Sciences,Università della Svizzera Italiana

Tags

Parkinson’s DiseaseSkin BiopsyAlpha Synuclein AggregatesPeripheral Nerve FibersImmunofluorescence AssayCryoprotectantCryosectioningBiomarkerPathogenesis

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Vacchi, E., Pinton, S., Kaelin-Lang, A., Melli, G. Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay. J. Vis. Exp. (148), e59558, doi:10.3791/59558 (2019).

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