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Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay
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Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay
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October 18, 2016
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Microglial phagocytosis is critical for the maintenance of tissue homeostasis and inadequate phagocytic function has been implicated in pathology. However, assessing microglia function in vivo is technically challenging. We have developed a simple but robust technique for precisely monitoring and quantifying the phagocytic potential of microglia in a physiological setting.
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Murinello, S., Moreno, S. K., Macauley, M. S., Sakimoto, S., Westenskow, P. D., Friedlander, M. Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay. J. Vis. Exp. (116), e54677, doi:10.3791/54677 (2016).
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