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13:42 min
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March 08, 2013
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Summary
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所提出的方法提供了一种方法扩张型心肌病的患者血浆中的检测功能有效的心性自体抗体，不论特异性抗原，通过分析隔离病人免疫球蛋白对大鼠离体心肌细胞的缩短及细胞内钙瞬变的影响。
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MeasurementAntibody EffectsCellular FunctionIsolated CardiomyocytesDilated CardiomyopathyHeart FailureGenetic DispositionToxic SubstancesAutoantibodiesCardiac EpitopesOnset And ProgressionDiseaseHemodynamic ImprovementImmunoadsorptionSpecific AntigensImmunoassaysStimulating AutoantibodiesBlocking AutoantibodiesCardiotropic AntibodiesFunctional RegionsCardiac Proteins
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Cite this Article
Eckerle, L. G., Felix, S. B., Herda, L. R. Measurement of Antibody Effects on Cellular Function of Isolated Cardiomyocytes. J. Vis. Exp. (73), e4237, doi:10.3791/4237 (2013).
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