The present protocol describes an assay to determine response to levamisole, a pharmacological agonist of one class of Caenorhabditis elegans acetylcholine receptors. In this liquid levamisole swim assay, researchers visually observe and quantitate the time-dependent paralysis of animals cultivated in 24-well plates.
Davis, A. N., Tanis, J. E. Measuring Caenorhabditis elegans Sensitivity to the Acetylcholine Receptor Agonist Levamisole. J. Vis. Exp. (184), e64056, doi:10.3791/64056 (2022).