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Measuring Caenorhabditis elegans Sensitivity to the Acetylcholine Receptor Agonist Levamisole
JoVE 杂志
遗传学
This content is Free Access.
JoVE 杂志 遗传学
Measuring Caenorhabditis elegans Sensitivity to the Acetylcholine Receptor Agonist Levamisole

Measuring Caenorhabditis elegans Sensitivity to the Acetylcholine Receptor Agonist Levamisole

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08:11 min

June 07, 2022

DOI:

08:11 min
June 07, 2022

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Summary

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The present protocol describes an assay to determine response to levamisole, a pharmacological agonist of one class of Caenorhabditis elegans acetylcholine receptors. In this liquid levamisole swim assay, researchers visually observe and quantitate the time-dependent paralysis of animals cultivated in 24-well plates.

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