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Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice
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Neurosciences
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Journal JoVE Neurosciences
Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice

2,714 Views

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07:49 min

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June 02, 2022

DOI:

10.3791/63972-v

DOI:
10.3791/63972-v

•

07:49 min
June 02, 2022

•

4 Views
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1Institute of Basic Medical Sciences, College of Medicine,National Cheng Kung University, 2Department of Physiology, College of Medicine,National Cheng Kung University

Summary

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Gut-derived microbial metabolites have multifaceted effects leading to complex behavior in animals. We aim to provide a step-by-step method to delineate the effects of gut-derived microbial metabolites in the brain via intracerebroventricular delivery via a guide cannula.

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Cite this Article

Liou, C., Yao, T., Wu, W. Intracerebroventricular Delivery of Gut-Derived Microbial Metabolites in Freely Moving Mice. J. Vis. Exp. (184), e63972, doi:10.3791/63972 (2022).

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