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细菌种群中分层基因型和辅助基因组位点的启发式挖掘

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Génétique

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Journal JoVE Génétique

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

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细菌种群中分层基因型和辅助基因组位点的启发式挖掘

1,872 Views

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08:03 min

•

December 07, 2021

DOI:

10.3791/63115-v

DOI:

10.3791/63115-v

•

08:03 min

December 07, 2021

•

3 Views

Natasha Pavlovikj*¹, Joao Carlos Gomes-Neto*^2,3, Andrew K. Benson^2,3

¹Department of Computer Science and Engineering,University of Nebraska-Lincoln, ²Department of Food Science and Technology,University of Nebraska-Lincoln, ³Nebraska Food for Health Center,University of Nebraska-Lincoln

Summary

该分析计算平台为对细菌种群基因组学感兴趣的微生物学家，生态学家和流行病学家提供实用指导。具体而言，这里介绍的工作展示了如何执行：i）分层基因型的系统发育指导映射;ii）基于频率的基因型分析;iii）亲属关系和克隆性分析;iv）识别谱系分化附属位点。

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