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Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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JoVE Revista Genética
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

DOI:
10.3791/63115-v

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08:03 min

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December 07, 2021

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, ,
1Department of Computer Science and Engineering,University of Nebraska-Lincoln, 2Department of Food Science and Technology,University of Nebraska-Lincoln, 3Nebraska Food for Health Center,University of Nebraska-Lincoln

Capítulos

  • 00:04Introduction
  • 02:23Conduct Analyses and Generate Visualizations
  • 05:17Results: Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Salmonella enterica
  • 06:58Conclusion

Summary

Traducción Automática

Traducción Automática

This analytical computational platform provides practical guidance for microbiologists, ecologists, and epidemiologists interested in bacterial population genomics. Specifically, the work presented here demonstrated how to perform: i) phylogeny-guided mapping of hierarchical genotypes; ii) frequency-based analysis of genotypes; iii) kinship and clonality analyses; iv) identification of lineage differentiating accessory loci.

Tags

Heuristic MiningHierarchical GenotypesAccessory Genome LociBacterial PopulationsProkEvoComputational PlatformScalable AnalysisPan-genomic ContentGenotype MappingPathogenic LineagesPublic Health SurveillanceBacterial Population GenomicsGigi TreePhylogenetic TreeData Aggregation

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