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Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis

Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis

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08:27 min

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September 02, 2021

DOI:

10.3791/62699-v

DOI:
10.3791/62699-v

•

08:27 min
September 02, 2021

•

7 Views
,
1Geriatrics Research Education and Clinical Center,Veterans Affairs Puget Sound Health Care System, 2Division of Gerontology and Geriatric Medicine, Department of Medicine,University of Washington

Summary

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This protocol describes two sensitive assays for discriminating among mild, moderate, and severe motor impairment in C. elegans models of amyotrophic lateral sclerosis, with general utility for C. elegans strains, with altered motility.

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Cite this Article

Currey, H. N., Liachko, N. F. Evaluation of Motor Impairment in C. elegans Models of Amyotrophic Lateral Sclerosis. J. Vis. Exp. (175), e62699, doi:10.3791/62699 (2021).

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