Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium

Kiyoharu  J. Miyagishima; Congxiao Zhang; Volha  V. Malechka; Kapil Bharti; Wei Li

doi:10.3791/61491

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Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium

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Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium

4,953 Views

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09:10 min

•

July 14, 2020

DOI:

10.3791/61491-v

DOI:

10.3791/61491-v

•

09:10 min

July 14, 2020

•

19 Views

Kiyoharu J. Miyagishima¹, Congxiao Zhang*², Volha V. Malechka*³, Kapil Bharti², Wei Li¹

¹Retinal Neurophysiology Section, National Eye Institute,National Institutes of Health, ²Ocular and Stem Cell Translational Research Section, National Eye Institute,National Institutes of Health, ³Human Visual Function Core, National Eye Institute,National Institutes of Health

Summary

Here, we present a method for recording light-evoked electrical responses of the retinal pigment epithelium (RPE) in mice using a technique known as DC-ERGs first described by Marmorstein, Peachey, and colleagues in the early 2000s.

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Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium

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