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Esecuzione di Xenografi muscolari scheletrici umani in topi immunodeficienti
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Biologie du développement
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Journal JoVE Biologie du développement
Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice
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Esecuzione di Xenografi muscolari scheletrici umani in topi immunodeficienti

9,445 Views

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07:48 min

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September 16, 2019

DOI:

10.3791/59966-v

DOI:
10.3791/59966-v

•

07:48 min
September 16, 2019

•

10 Views
, , ,
1Graduate Program in Cellular and Molecular Medicine,Johns Hopkins University School of Medicine, 2Department of Neurology,Johns Hopkins University School of Medicine, 3Kennedy Krieger Institute, 4Department of Neuroscience,Johns Hopkins University School of Medicine

Summary

Automatically generated

Le malattie umane complesse possono essere difficili da modellare nei sistemi di modelli di laboratorio tradizionali. Qui, descriviamo un approccio chirurgico per modellare la malattia muscolare umana attraverso il trapianto di biopsie muscolari scheletriche umane in topi immunodeficienti.

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Cite this Article

Britson, K. A., Black, A. D., Wagner, K. R., Lloyd, T. E. Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice. J. Vis. Exp. (151), e59966, doi:10.3791/59966 (2019).

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