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Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria
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September 16, 2013
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Isolation and characterization of the lipid A domain of lipopolysaccharide (LPS) from gram-negative bacteria provides insight into cell surface based mechanisms of antibiotic resistance, bacterial survival and fitness, and how chemically diverse lipid A molecular species differentially modulate host innate immune responses.
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Henderson, J. C., O'Brien, J. P., Brodbelt, J. S., Trent, M. S. Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria. J. Vis. Exp. (79), e50623, doi:10.3791/50623 (2013).
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