Waiting
Traitement de la connexion…

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / Progenitor-derived Oligodendrocyte Culture System …
JoVE Journal
Neuroscience

Un abonnement à JoVE est nécessaire pour afficher ce contenu. Connectez-vous ou commencez votre essai gratuit.

JoVE Journal Neuroscience
Progenitor-derived Oligodendrocyte Culture System from Human Fetal Brain
 

Progenitor-derived Oligodendrocyte Culture System from Human Fetal Brain

Article DOI: 10.3791/4274-v • 14:26 min • December 20th, 2012
December 20th, 2012 •
1, 2, 1, 1, 1, 1
1Laboratory of Molecular Medicine and Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 2Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health

Chapitres

résumé
Automatic Translation

Primary, human fetal brain-derived, multipotential progenitor cells proliferate in vitro while maintaining the capacity to differentiate into neurons and astrocytes. This work shows that neural progenitors can be induced to differentiate through stages of the oligodendrocytic lineage by conditioning with select growth factors.

Tags

Progenitor-derived Oligodendrocyte Culture System Human Fetal Brain Differentiation Neural Progenitors Neuronal Cell Types Glial Cell Types Molecular Regulation Neural Cell Lineage Development In Vitro Expansion CNS Tissue Glial Progenitors Sub-cortical White Matter Culture Conditions Myelin Producing Oligodendrocytes Galactocerebroside+ O4+ Oligodendrocyte Precursor Or Progenitor Cells (OPC) Neural Precursor Cells Support Cells (astrocytes And Neurons) Culture System In Vitro Experimentation Primary Human Oligodendrocytes Pathogenesis Neurotropic Infectious Agents (human Polyomavirus JCV) Demyelinating Diseases Central Nervous System (CNS)
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter