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A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain

Journal JoVE
Neurosciences

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Journal JoVE Neurosciences

A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain

A Polished and Reinforced Thinned-skull Window for Long-term Imaging of the Mouse Brain

26,357 Views

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09:49 min

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March 07, 2012

DOI:

DOI:

•

09:49 min

March 07, 2012

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6 Views

Andy Y. Shih, Celine Mateo, Patrick J. Drew³, Philbert S. Tsai, David Kleinfeld⁴

¹Department of Physics,University of California, San Diego, ²Department of Engineering Science and Mechanics,Pennsylvania State University , ³Department of Neurosurgery,Pennsylvania State University , ⁴Section of Neurobiology,University of California, San Diego

Tags

Polished And Reinforced Thinned-skull Window Long-term Imaging Mouse Brain In Vivo Imaging Cortical Function Optical Access Intracranial Environment PoRTS Window Optical Clarity Bone Regrowth Inhibition Light Scattering Reduction Inflammation Reduction Two-photon Laser Scanning Microscopy Cerebral Blood Flow Cellular Function Anesthetized Preparations Awake Preparations Optogenetics Blood Flow Disruption

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