Here, we present an effective and efficient method for rodent tail vein injections using a uniquely designed warming/restraining device. By streamlining the initiation of vasodilation and restraining processes, this protocol allows accurate and timely intravenous injections of large groups of animals with minimal distress.
Yano, J., Lilly, E. A., Noverr, M. C., Fidel, P. L. A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model. J. Vis. Exp. (165), e61961, doi:10.3791/61961 (2020).