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Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish
JoVE Revista
Inmunología y contagio
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JoVE Revista Inmunología y contagio
Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

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07:00 min

October 08, 2018

DOI:

07:00 min
October 08, 2018

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Summary

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Here, we present a protocol to model human tuberculosis in an adult zebrafish using its natural pathogen Mycobacterium marinum. Extracted DNA and RNA from the internal organs of infected zebrafish can be used to reveal the total mycobacterial loads in the fish and the host's immune responses with qPCR.

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