需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish
10,285 Views
•
07:00 min
•
October 08, 2018
DOI:
Summary
Automatically generated
Here, we present a protocol to model human tuberculosis in an adult zebrafish using its natural pathogen Mycobacterium marinum. Extracted DNA and RNA from the internal organs of infected zebrafish can be used to reveal the total mycobacterial loads in the fish and the host's immune responses with qPCR.
Explore More Videos
Read Article
Cite this Article
Luukinen, H., Hammarén, M. M., Vanha-aho, L., Parikka, M. Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish. J. Vis. Exp. (140), e58299, doi:10.3791/58299 (2018).
Copy