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JoVE Journal
Bioengineering

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A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces
 

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces

Article DOI: 10.3791/55362-v 12:04 min March 1st, 2017
March 1st, 2017

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Resumen

Cell differentiation is regulated by a host of microenvironmental factors, including both matrix composition and substrate material properties. We describe here a technique utilizing cell microarrays in conjunction with traction force microscopy to evaluate both cell differentiation and biomechanical cell–substrate interactions as a function of microenvironmental context.

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