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In Situ Characterization of Hydrated Proteins in Water by SALVI and ToF-SIMS
 

In Situ Characterization of Hydrated Proteins in Water by SALVI and ToF-SIMS

Article DOI: 10.3791/53708-v • 09:48 min • February 15th, 2016
February 15th, 2016 •
1, *2, *1, 2, 1
1Fundamental & Computational Sciences Directorate, Pacific Northwest National Laboratory, 2Wiley Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory
* These authors contributed equally

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This work presents a protocol for liquid handling and sample introduction to a microchannel for in situ time-of-flight secondary ion mass spectrometry analysis of protein biomolecules in an aqueous solution.

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Keywords: In Situ Characterization Hydrated Proteins Water SALVI ToF-SIMS Biomolecules Biointerface Solid-liquid Interface Cancer Cells Drug Interactions Biofilms Fibronectin Silicon Wafer Silicon Nitride Membrane
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