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Mirare i farmaci ai macrofagi di pesce zebra larvale iniettando liposomi caricati con droga
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Immunologie und Infektion
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JoVE Journal Immunologie und Infektion
Targeting Drugs to Larval Zebrafish Macrophages by Injecting Drug-Loaded Liposomes
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Mirare i farmaci ai macrofagi di pesce zebra larvale iniettando liposomi caricati con droga

7,456 Views

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11:31 min

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February 18, 2020

DOI:

10.3791/60198-v

DOI:
10.3791/60198-v

•

11:31 min
February 18, 2020

•

7 Views
, , , , ,
1Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences,University of Auckland, 2School of Pharmacy, Faculty of Medical and Health Sciences,University of Auckland, 3School of Medicine, Faculty of Medical and Health Sciences,University of Auckland

Summary

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Qui, descriviamo la sintesi dei liposomi caricati dai farmaci e la loro microiniezione nel pesce zebra larvale allo scopo di indirizzare la somministrazione di farmaci alle cellule di macrofago-lignaggio.

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LiposomesMacrophagesZebrafishDrug DeliveryMitochondrial Reactive Oxygen SpeciesPoloxamer 188ExtrusionUltracentrifugationLive Cell Imaging

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Cite this Article

Linnerz, T., Kanamala, M., Astin, J. W., Dalbeth, N., Wu, Z., Hall, C. J. Targeting Drugs to Larval Zebrafish Macrophages by Injecting Drug-Loaded Liposomes. J. Vis. Exp. (156), e60198, doi:10.3791/60198 (2020).

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