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通过自由浮动免疫荧光测定,在皮外神经纤维中定位阿尔法核糖核酸聚合体
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JoVE Journal Neurowissenschaften
Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
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通过自由浮动免疫荧光测定,在皮外神经纤维中定位阿尔法核糖核酸聚合体

7,959 Views

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08:33 min

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June 25, 2019

DOI:

10.3791/59558-v

DOI:
10.3791/59558-v

•

08:33 min
June 25, 2019

•

3 Views
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1Laboratory for Biomedical Neurosciences,Neurocenter of Southern Switzerland, 2Neurology Department,Neurocenter of Southern Switzerland, 3Department of Neurology, Inselspital, Bern University Hospital,University of Bern, 4Faculty of Biomedical Sciences,Università della Svizzera Italiana

Tags

Parkinson’s DiseaseSkin BiopsyAlpha Synuclein AggregatesPeripheral Nerve FibersImmunofluorescence AssayCryoprotectantCryosectioningBiomarkerPathogenesis

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Vacchi, E., Pinton, S., Kaelin-Lang, A., Melli, G. Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay. J. Vis. Exp. (148), e59558, doi:10.3791/59558 (2019).

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