/
/
A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
10,357 Views
•
09:15 min
•
February 28, 2019
DOI:
Summary
Automatically generated
An approach is described for real-time detection of the innate immune response to cutaneous wounding and Staphylococcus aureus infection of mice. By comparing LysM-EGFP mice (which possess fluorescent neutrophils) with a LysM-EGFP crossbred immunodeficient mouse strain, we advance our understanding of infection and the development of approaches to combat infection.
Read Article
Cite this Article
Anderson, L. S., Reynolds, M. B., Rivara, K. R., Miller, L. S., Simon, S. I. A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection. J. Vis. Exp. (144), e59015, doi:10.3791/59015 (2019).
Copy