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A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
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February 28, 2019
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An approach is described for real-time detection of the innate immune response to cutaneous wounding and Staphylococcus aureus infection of mice. By comparing LysM-EGFP mice (which possess fluorescent neutrophils) with a LysM-EGFP crossbred immunodeficient mouse strain, we advance our understanding of infection and the development of approaches to combat infection.
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Anderson, L. S., Reynolds, M. B., Rivara, K. R., Miller, L. S., Simon, S. I. A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection. J. Vis. Exp. (144), e59015, doi:10.3791/59015 (2019).
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