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Preparation of Exosomes for siRNA Delivery to Cancer Cells
JoVE Journal
Krebsforschung
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JoVE Journal Krebsforschung
Preparation of Exosomes for siRNA Delivery to Cancer Cells

Preparation of Exosomes for siRNA Delivery to Cancer Cells

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09:59 min

December 05, 2018

DOI:

09:59 min
December 05, 2018

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Summary

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An exosome is a new generation of drug delivery carriers. We established an exosome isolation protocol with high yield and purity for siRNA delivery. We also encapsulated fluorescently labelled non-specific siRNA into exosomes and investigated the cellular uptake of siRNA-loaded exosomes in cancer cells.

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