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Preparation of Exosomes for siRNA Delivery to Cancer Cells
JoVE 杂志
癌症研究
This content is Free Access.
JoVE 杂志 癌症研究
Preparation of Exosomes for siRNA Delivery to Cancer Cells

Preparation of Exosomes for siRNA Delivery to Cancer Cells

23,961 Views

09:59 min

December 05, 2018

DOI:

09:59 min
December 05, 2018

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Summary

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An exosome is a new generation of drug delivery carriers. We established an exosome isolation protocol with high yield and purity for siRNA delivery. We also encapsulated fluorescently labelled non-specific siRNA into exosomes and investigated the cellular uptake of siRNA-loaded exosomes in cancer cells.

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