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在秀丽线虫中对倍体的操控

JoVE Journal
Genetik

This content is Free Access.

JoVE Journal Genetik

Manipulation of Ploidy in Caenorhabditis elegans

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在秀丽线虫中对倍体的操控

10,613 Views

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07:54 min

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March 15, 2018

DOI:

10.3791/57296-v

DOI:

10.3791/57296-v

•

07:54 min

March 15, 2018

•

10 Views

Erlyana K. Clarke¹, Katherine A. Rivera Gomez^1,2, Zaki Mustachi¹, Mikaela C. Murph^1,3, Mara Schvarzstein^1,2,3

¹Brooklyn College, Biology Department,City University of New York, ²The Graduate Center, Biology Department,City University of New York, ³Advanced Science Research Center,City University of New York

Summary

这种方法允许生成二、四倍体杂交和无菌的秀丽线虫从任何双倍菌株。这种方法产生的多倍体菌株用于研究减数分裂前期的染色体相互作用, 这一方法对于研究细胞、发育、进化和肿瘤生物学等重要的基本问题是有用的。

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