Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

Ana R. Leda; Levy Dygert; Luc Bertrand; Michal Toborek

doi:10.3791/54804

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Souris microchirurgie Infusion Technique pour ciblée Substance Livraison dans le SNC via L'artère carotide interne

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Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery

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Souris microchirurgie Infusion Technique pour ciblée Substance Livraison dans le SNC via L'artère carotide interne

10,622 Views

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06:41 min

•

January 31, 2017

DOI:

10.3791/54804-v

DOI:

10.3791/54804-v

•

06:41 min

January 31, 2017

•

8 Views

Ana R. Leda¹, Levy Dygert¹, Luc Bertrand¹, Michal Toborek^1,2

¹Department of Biochemistry and Molecular Biology, Miller School of Medicine,University of Miami, ²The Jerzy Kukuczka Academy of Physical Education

Summary

The present protocol describes a mouse microsurgery infusion technique, which effectively delivers substances directly into the brain via the internal carotid artery.

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Mouse Microsurgery Infusion Technique Targeted Substance Delivery CNS Internal Carotid Artery Neurowissenschaften Drug Delivery Pathogen Exosome Minimal Trauma Neuronal Network Brain Concentration Anesthesia Surgical Procedure Common Carotid Artery External Carotid Artery Internal Carotid Artery Vessel Clips

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Souris microchirurgie Infusion Technique pour ciblée Substance Livraison dans le SNC<i> via</i> L'artère carotide interne

Summary

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