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깨어 쥐의 구강 내 Tastant 관리하는 동안 빠른 스캔 순환 전압 전류 법으로 빠른 도파민 역학 시험
JoVE Journal
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JoVE Journal Verhalten
Examination of Rapid Dopamine Dynamics with Fast Scan Cyclic Voltammetry During Intra-oral Tastant Administration in Awake Rats
DOI:

10:44 min

August 12, 2015

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Kapitel

  • 00:05Titel
  • 01:56Fabricating the Electrodes
  • 04:14Fabricating Oral Catheters
  • 05:24Combined Intraoral Surgery and Intracranial Cannulation Surgery
  • 07:16Taking Voltametric Recordings in Awake, Freely Moving Rats
  • 08:52Results: Tastant Stimulated Dopamine Release Measured in the NAc
  • 10:11Conclusion

Summary

Automatische Übersetzung

Rapid fluctuations in extracellular dopamine (DA) mediate both reward processing and motivated behavior in mammals. This manuscript describes the combined use of fast scan cyclic voltammetry (FSCV) and intra-oral tastant administration to determine how tastants alter rapid dopamine release in awake, freely moving rats.

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