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神经干细胞和祖细胞在小鼠脑开发基因毒性应激后的评估细胞周期进程
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JoVE Journal Neurowissenschaften
Assessing Cell Cycle Progression of Neural Stem and Progenitor Cells in the Mouse Developing Brain after Genotoxic Stress
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神经干细胞和祖细胞在小鼠脑开发基因毒性应激后的评估细胞周期进程

15,110 Views

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09:51 min

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May 07, 2014

DOI:

10.3791/51209-v

DOI:
10.3791/51209-v

•

09:51 min
May 07, 2014

•

9 Views
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1Laboratoire de Radiopathologie,CEA DSV iRCM SCSR, 2INSERM, U967, 3Université Paris Diderot, Sorbonne Paris Cité, 4Université Paris Sud, UMR 967

Summary

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胸苷两个类似物管理，埃杜和BrdU，在孕鼠允许在神经细胞和祖细胞在胚胎小鼠大脑细胞周期进程的分析。这个方法是有用的，以确定基因毒性应激，包括电离辐射，脑发育过程中的作用。

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Cite this Article

Etienne, O., Bery, A., Roque, T., Desmaze, C., Boussin, F. D. Assessing Cell Cycle Progression of Neural Stem and Progenitor Cells in the Mouse Developing Brain after Genotoxic Stress. J. Vis. Exp. (87), e51209, doi:10.3791/51209 (2014).

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