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Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells
JoVE 杂志
生物工程
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JoVE 杂志 生物工程
Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells

Rapid Antibody Glycoengineering in Chinese Hamster Ovary Cells

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06:53 min

June 02, 2022

DOI:

06:53 min
June 02, 2022

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Summary

Automatically generated

The glycosylation pattern of an antibody determines its clinical performance, thus industrial and academic efforts to control glycosylation persist. Since typical glycoengineering campaigns are time- and labor-intensive, the generation of a rapid protocol to characterize the impact of glycosylation genes using transient silencing would prove useful.

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